Title : Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor.

Pub. Date : 2015 May 25

PMID : 25824408






1 Functional Relationships(s)
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1 Among several important phosphorylation sites in cytoplasmic EGFR, Rg3 increased the phosphorylation of tyrosine 1045 (pY1045) and serine 1046/1047 (pS1046/1047) for EGFR degradation and coincidently, attenuated pY1173 and pY1068 for mitogen-activated protein kinase activity. Serine epidermal growth factor receptor Homo sapiens