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32455838 | Cardio-Metabolic Effects of High-Fat Diets and Their Underlying Mechanisms-A Narrative Review. | 2020 May 21 |
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33003449 | Ceramide-Enriched Membrane Domains Contribute to Targeted and Nontargeted Effects of Radiation through Modulation of PI3K/AKT Signaling in HNSCC Cells. | 2020 Sep 29 |
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29470962 | Indomethacin induced glioma apoptosis involving ceramide signals. | 2018 Apr 1 |
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29071793 | Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content is Related to Insulin Sensitivity After 8 Weeks of Overfeeding. | 2017 Dec |
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26698173 | Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE. | 2016 Feb 5 |
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26897748 | C6 ceramide sensitizes the anti-hepatocellular carcinoma (HCC) activity by AZD-8055, a novel mTORC1/2 dual inhibitor. | 2016 Aug |
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| 7 |
27852416 | [Effects and mechanism ofitraconazole on prostate cancer PC-3 cell apoptosis]. | 2016 Oct 25 |
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| 8 |
25380816 | Akt/eNOS signaling pathway mediates inhibition of endothelial progenitor cells by palmitate-induced ceramide. | 2015 Jan 1 |
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| 9 |
25576381 | C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: a mechanism study. | 2015 Mar 1 |
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| 10 |
26090071 | Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation. | 2015 |
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26115843 | Inhibition of GSK3β by pharmacological modulation of sphingolipid metabolism occurs independently of ganglioside disturbance in a cellular model of Alzheimer's disease. | 2015 Sep |
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26201515 | Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response. | 2015 Oct 1 |
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26379195 | SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α. | 2015 Sep 17 |
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| 14 |
26446703 | Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets. | 2015 Oct 8 |
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| 15 |
24079644 | Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress. | 2014 Mar |
3 |
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24420784 | Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate. | 2014 Aug |
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24650522 | Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. | 2014 Jul |
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| 18 |
25058613 | Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight. | 2014 |
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25152399 | C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells. | 2014 Sep 12 |
3 |
| 20 |
23457308 | Ceramide mediates inhibition of the Akt/eNOS pathway by high levels of glucose in human vascular endothelial cells. | 2013 |
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| 21 |
23835113 | Role of ceramide in diabetes mellitus: evidence and mechanisms. | 2013 Jul 8 |
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24073738 | Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. | 2013 Dec 15 |
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24269881 | Metformin limits ceramide-induced senescence in C2C12 myoblasts. | 2013 Nov-Dec |
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| 24 |
22320914 | Alcohol, insulin resistance and the liver-brain axis. | 2012 Mar |
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22383528 | Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt. | 2012 Apr 20 |
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| 26 |
22583777 | Co-administration phenoxodiol with doxorubicin synergistically inhibit the activity of sphingosine kinase-1 (SphK1), a potential oncogene of osteosarcoma, to suppress osteosarcoma cell growth both in vivo and in vitro. | 2012 Aug |
5 |
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22652149 | Ceramide biosynthesis and metabolism in trophoblast syncytialization. | 2012 Oct 15 |
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| 28 |
22764099 | Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine. | 2012 Jul 5 |
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23019415 | Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1. | 2012 Sep |
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| 30 |
19959757 | Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling. | 2010 Mar |
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20954073 | Ceramide produces apoptosis through induction of p27(kip1) by protein phosphatase 2A-dependent Akt dephosphorylation in PC-3 prostate cancer cells. | 2010 |
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18996148 | Regulation of ceramide-induced neuronal death: cell metabolism meets neurodegeneration. | 2009 Mar |
2 |
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19103588 | Phosphatidylinositol 3-kinase/AKT pathway regulates the endoplasmic reticulum to golgi traffic of ceramide in glioma cells: a link between lipid signaling pathways involved in the control of cell survival. | 2009 Feb 20 |
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19721393 | Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells. | 2009 Sep |
4 |
| 35 |
18054155 | Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells. | 2008 Feb 18 |
2 |
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18397976 | Muscle adaptation to short-term fasting in healthy lean humans. | 2008 Jul |
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17259384 | Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells. | 2007 Feb |
3 |
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17471535 | PKB/Akt inhibits ceramide-induced apoptosis in neuroblastoma cells by blocking apoptosis-inducing factor (AIF) translocation. | 2007 Dec 1 |
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17666435 | GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis. | 2007 Aug 15 |
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| 40 |
17225464 | Induction of apoptotic cell death by a ceramide analog in PC-3 prostate cancer cells. | 2006 Dec |
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| 41 |
15781658 | Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species. | 2005 Mar 15 |
2 |
| 42 |
15968641 | Ceramide regulation of the tumor suppressor phosphatase PTEN in rafts isolated from neurotumor cell lines. | 2005 Aug 15 |
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| 43 |
15978590 | Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway. | 2005 Jul 4 |
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| 44 |
16290312 | IGF-I protects cortical neurons against ceramide-induced apoptosis via activation of the PI-3K/Akt and ERK pathways; is this protection independent of CREB and Bcl-2? | 2005 Dec 14 |
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14693694 | Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. | 2004 Jan |
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| 46 |
15220355 | Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. | 2004 Aug 27 |
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15361788 | Acid sphingomyelinase in macrophage apoptosis. | 2004 Oct |
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| 48 |
12525490 | A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. | 2003 Mar 21 |
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| 49 |
12676512 | Intracellular signal transduction pathways activated by ceramide and its metabolites. | 2003 May |
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12691738 | Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. | 2003 Mar |
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