Title : Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets.

Pub. Date : 2015 Oct 8

PMID : 26446703






1 Functional Relationships(s)
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1 Furthermore, in silico mutation studies and experimental validations led to a novel finding that concurrently targeting ceramide and PI3K/AKT pathway by chemical probes or marketed drugs achieves synergistic anti-cancer effects. Ceramides AKT serine/threonine kinase 1 Homo sapiens