Title : Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway.

Pub. Date : 2005 Jul 4

PMID : 15978590






1 Functional Relationships(s)
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1 Based on these and our previous observations, we propose a working model for C1P in which inhibition of acid sphingomyelinase and the subsequent decrease in ceramide levels would allow cell signaling through stimulation of the PI3-K/PKB pathway to promote cell survival. Ceramides AKT serine/threonine kinase 1 Homo sapiens