Pub. Date : 2009 Mar
PMID : 18996148
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The early inhibition of the neuronal survival pathway regulated by phosphatidil-inositol-3-kinase/protein kinase B or AKT mediated by ceramide may be a relevant early event in the decision of neuronal survival/death. | Ceramides | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Subtle and early metabolic alterations caused by inhibition of the PI3K/AKT pathway mediated by ceramide may potentially work with genes associated with neurodegenerative diseases such as Parkinson"s and Alzheimer"s disease. | Ceramides | AKT serine/threonine kinase 1 | Homo sapiens |