219 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 26870244 | Integrin β1-mediated acquired gefitinib resistance in non-small cell lung cancer cells occurs via the phosphoinositide 3-kinase-dependent pathway. | 2016 Jan | 4 |
52 | 27125283 | Anticancer Effects of Paris Saponins by Apoptosis and PI3K/AKT Pathway in Gefitinib-Resistant Non-Small Cell Lung Cancer. | 2016 Apr 29 | 1 |
53 | 27283902 | PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells. | 2016 Aug 2 | 1 |
54 | 27346398 | [Effect of autophagy inhibitor combined with EGFR inhibitor on triple-negative breast cancer MDA-MB-468 and MDA-MB-231 cells]. | 2016 Jun 23 | 2 |
55 | 27347100 | Gefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathway. | 2016 Jul | 3 |
56 | 27494877 | FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop. | 2016 Sep 13 | 1 |
57 | 27629794 | Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation. | 2016 Nov | 1 |
58 | 27690301 | MiR-128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the c-met/PI3K/AKT pathway. | 2016 Nov 8 | 2 |
59 | 27698894 | AKT-STAT3 Pathway as a Downstream Target of EGFR Signaling to Regulate PD-L1 Expression on NSCLC cells. | 2016 | 2 |
60 | 27716616 | Ran GTPase promotes cancer progression via Met recepto-rmediated downstream signaling. | 2016 Nov 15 | 1 |
61 | 27877053 | Synergistic activity of vorinostat combined with gefitinib but not with sorafenib in mutant KRAS human non-small cell lung cancers and hepatocarcinoma. | 2016 | 1 |
62 | 27989877 | Chinese herbal medicine Fuzheng Kang-Ai decoction sensitized the effect of gefitinib on inhibition of human lung cancer cells through inactivating PI3-K/Akt -mediated suppressing MUC1 expression. | 2016 Dec 24 | 3 |
63 | 28101246 | Detection of microRNA-200b may predict the inhibitory effect of gefitinib on non-small cell lung cancer and its potential mechanism. | 2016 Dec | 1 |
64 | 25454348 | Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer. | 2015 Feb | 1 |
65 | 25488183 | Enoxaparin sensitizes human non-small-cell lung carcinomas to gefitinib by inhibiting DOCK1 expression, vimentin phosphorylation, and Akt activation. | 2015 | 1 |
66 | 25588160 | Combination of SF1126 and gefitinib induces apoptosis of triple-negative breast cancer cells through the PI3K/AKT-mTOR pathway. | 2015 Apr | 4 |
67 | 25653196 | EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line. | 2015 Apr | 1 |
68 | 25662161 | Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells. | 2015 May 15 | 6 |
69 | 25674002 | NVP-BEZ235 overcomes gefitinib-acquired resistance by down-regulating PI3K/AKT/mTOR phosphorylation. | 2015 | 2 |
70 | 26063323 | Norcantharidin combined with EGFR-TKIs overcomes HGF-induced resistance to EGFR-TKIs in EGFR mutant lung cancer cells via inhibition of Met/PI3k/Akt pathway. | 2015 Aug | 1 |
71 | 26176330 | The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors. | 2015 | 1 |
72 | 26203858 | Reciprocal positive regulation between Cx26 and PI3K/Akt pathway confers acquired gefitinib resistance in NSCLC cells via GJIC-independent induction of EMT. | 2015 Jul 23 | 3 |
73 | 26517520 | 244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells. | 2015 Dec 29 | 1 |
74 | 26622906 | Synergistic interaction between MEK inhibitor and gefitinib in EGFR-TKI-resistant human lung cancer cells. | 2015 Oct | 2 |
75 | 24268810 | Fulvestrant increases gefitinib sensitivity in non-small cell lung cancer cells by upregulating let-7c expression. | 2014 Apr | 1 |
76 | 24374738 | The PI3K/AKT pathway promotes gefitinib resistance in mutant KRAS lung adenocarcinoma by a deacetylase-dependent mechanism. | 2014 Jun 1 | 3 |
77 | 24486412 | Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells. | 2014 May | 1 |
78 | 24631288 | Effect of simvastatin on the resistance to EGFR tyrosine kinase inhibitors in a non-small cell lung cancer with the T790M mutation of EGFR. | 2014 May 1 | 1 |
79 | 24840891 | Combined gefitinib and pemetrexed overcome the acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. | 2014 Aug | 1 |
80 | 24884778 | Enhancement of gefitinib-induced growth inhibition by Marsdenia tenacissima extract in non-small cell lung cancer cells expressing wild or mutant EGFR. | 2014 May 22 | 2 |
81 | 24957682 | AKT inhibition synergistically enhances growth-inhibitory effects of gefitinib and increases apoptosis in non-small cell lung cancer cell lines. | 2014 Aug | 1 |
82 | 25058005 | Alteration in Mir-21/PTEN expression modulates gefitinib resistance in non-small cell lung cancer. | 2014 | 2 |
83 | 25275600 | Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling. | 2014 Oct 2 | 1 |
84 | 25623760 | [Effect of recombinant human p53 adenovirus (Ad-p53) combined with EGFR inhibitor gefitinib on the sensitivity of breast cancer MDA-MB-468 cells]. | 2014 Dec | 2 |
85 | 23102728 | MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. | 2013 Feb | 1 |
86 | 23111983 | Apoptosis induced by benzyl isothiocyanate in gefitinib-resistant lung cancer cells is associated with Akt/MAPK pathways and generation of reactive oxygen species. | 2013 May | 1 |
87 | 23200321 | Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition. | 2013 Jun | 2 |
88 | 23270470 | Gefitinib-resistance is related to BIM expression in non-small cell lung cancer cell lines. | 2013 Mar | 1 |
89 | 23344263 | Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells. | 2013 Feb 15 | 1 |
90 | 23525575 | Combined inhibition of the EGFR and mTOR pathways in EGFR wild-type non-small cell lung cancer cell lines with different genetic backgrounds. | 2013 Jun | 1 |
91 | 23601074 | Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells. | 2013 May | 2 |
92 | 23714663 | [Small molecule inhibitor SB203580 enhances the antitumor effect of gefitinib in PC-9 and A549 lung cancer cell lines]. | 2013 Feb | 1 |
93 | 23849826 | Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by Gefitinib and Cetuximab triggered antibody-dependent cellular cytotoxicity. | 2013 Oct | 1 |
94 | 23959460 | Effects of pemetrexed, gefitinib, and their combination on human colorectal cancer cells. | 2013 Oct | 1 |
95 | 23962905 | Crizotinib overcomes hepatocyte growth factor-mediated resistance to gefitinib in EGFR-mutant non-small-cell lung cancer cells. | 2013 Nov | 1 |
96 | 24071646 | Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells. | 2013 Sep 26 | 2 |
97 | 24146879 | Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer. | 2013 | 1 |
98 | 24280348 | Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells. | 2013 Dec | 2 |
99 | 24325059 | [Effect of bufalin combined gefitinib on lung cancer H1975 cells and its mechanisms research]. | 2013 Aug | 1 |
100 | 24337846 | Effects of PI3K inhibitor NVP-BKM120 on acquired resistance to gefitinib of human lung adenocarcinoma H1975 cells. | 2013 Dec | 3 |