Title : Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.

Pub. Date : 2016 Nov

PMID : 27629794






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1 In summary, our results indicate that gefitinib effectively enhances TRAIL-induced apoptosis, likely via autophagy and JNK- mediated death receptor expression and phosphorylation of Akt and ERK. Gefitinib AKT serine/threonine kinase 1 Homo sapiens