Pub. Date : 2016 Dec
PMID : 28101246
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Upregulation of microRNA-200b led to the elevated sensitivity of glioma cells to gefitinib, and this effect may be explained as microRNA-200b being able to inhibit the expression of IGF-1R, thereby reducing the activation of downstream phosphoinositide 3-kinase/AKT and mitogen-activated protein kinase signaling pathways. | Gefitinib | AKT serine/threonine kinase 1 | Homo sapiens |