Tacrolimus

cytochrome P450 family 3 subfamily A member 5 ; Homo sapiens







489 Article(s)
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1 34241984 Development of De Novo Donor-specific HLA Antibodies and AMR in Renal Transplant Patients Depends on CYP3A5 Genotype. 2022 May 1 3
2 34362271 The CYP3A5 and ABCB1 Gene Polymorphisms in Kidney Transplant Patients and Establishment of Initial Daily Tacrolimus Dosing Formula. 2022 Apr 2
3 34583027 Impact of Pharmacogenetics on Intravenous Tacrolimus Exposure and Conversions to Oral Therapy. 2022 Jan 5
4 34688813 CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation. 2022 Jan 30 3
5 34708436 Beneficial effects of Wuzhi Capsule on tacrolimus blood concentrations in liver transplant patients with different donor-recipient CYP3A5 genotypes. 2022 Feb 2
6 34781138 Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients. 2022 Jan 2
7 34859357 The impact of cytochrome P450 3A5 genotype on early tacrolimus metabolism and clinical outcomes in lung transplant recipients. 2022 Apr 4
8 35103348 Race and sex associations with tacrolimus pharmacokinetics in stable kidney transplant recipients. 2022 Feb 2
9 35110472 Pharmacokinetics of tacrolimus following an overdose in a patient with extreme obesity and genotype CYP3A5*3/*3: a case report. 2022 1
10 35180322 Effect of hepar-protecting Wuzhi capsule on Pharmacokinetics and Dose-effect Character of Tacrolimus in Healthy Volunteers. 2022 Feb 18 3
11 35202484 PharmVar GeneFocus: CYP3A5. 2022 Feb 24 2
12 35220592 Population pharmacokinetics of tacrolimus in Chinese adult liver transplant patients. 2022 Apr 1
13 35238110 Personalized immunosuppression after kidney transplantation. 2022 Jun 2
14 35322385 Correction to: The impact of IL-10 and CYP3A5 gene polymorphisms on dose-adjusted trough blood tacrolimus concentrations in early post-renal transplant recipients. 2022 Jun 1
15 35389944 Composite CYP3A phenotypes influence tacrolimus dose-adjusted concentration in lung transplant recipients. 2022 Jul 1 4
16 35395919 Effect of drug combination on tacrolimus target dose in renal transplant patients with different CYP3A5 genotypes. 2022 Mar 9
17 35428510 CYP3a5 Genetic Polymorphism in Chinese Population With Renal Transplantation: A Meta-Analysis Review. 2022 Apr 2
18 35466485 Effects of tacrolimus intrapatient variability and CYP3A5 polymorphism on the outcomes of pediatric kidney transplantation. 2022 Apr 24 1
19 35536394 The pharmacokinetics of tacrolimus in peripheral blood mononuclear cells and limited sampling strategy for estimation of exposure in renal transplant recipients. 2022 May 10 2
20 35562875 Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach. 2022 Apr 19 1
21 35570009 Renal Cyp3a5-Expressing Genotype Decreases Tacrolimus-to-Dose Ratio in Small Cohort of Renal Transplant Recipients-Preliminary Report. 2022 May 12 8
22 35578867 Impact of POR*28 Variant on Tacrolimus Pharmacokinetics in Kidney Transplant Patients with Different CYP3A5 Genotypes. 2022 May 16 1
23 35629245 Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants. 2022 May 19 1
24 32803289 Diltiazem on tacrolimus exposure and dose sparing in Chinese pediatric primary nephrotic syndrome: impact of CYP3A4, CYP3A5, ABCB1, and SLCO1B3 polymorphisms. 2021 Jan 2
25 32843687 Influence of CYP3A polymorphisms on tacrolimus pharmacokinetics in kidney transplant recipients. 2021 Feb 1
26 32986876 Clinical significance of personalized tacrolimus dosing by adjusting to donor CYP3A-status in liver transplant recipients. 2021 Apr 2
27 33027230 Tacrolimus Exposure in Obese Patients: and A Case-Control Study in Kidney Transplantation. 2021 Apr 1 1
28 33248001 Temporary decrease in tacrolimus clearance in cytochrome P450 3A5 non-expressors early after living donor kidney transplantation: Effect of interleukin 6-induced suppression of the cytochrome P450 3A gene. 2021 Mar 3
29 33348024 Multiple microRNAs regulate tacrolimus metabolism through CYP3A5. 2021 Feb 5
30 33386894 The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose-corrected trough concentration in the early period after liver transplantation. 2021 Jun 2
31 33398393 CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients. 2021 Jun 2
32 33432012 Early impact of donor CYP3A5 genotype and Graft-to-Recipient Weight Ratio on tacrolimus pharmacokinetics in pediatric liver transplant patients. 2021 Jan 11 4
33 33515077 Correction to: CYP3A5 and CYP3A7 genetic polymorphisms affect tacrolimus concentration in pediatric patients with nephrotic syndrome. 2021 Aug 1
34 33649515 Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients. 2021 Jun 1
35 33654003 Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing. 2021 Oct 1 3
36 33673653 Investigation of the Impact of CYP3A5 Polymorphism on Drug-Drug Interaction between Tacrolimus and Schisantherin A/Schisandrin A Based on Physiologically-Based Pharmacokinetic Modeling. 2021 Feb 27 3
37 33692688 Commentary: The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients. 2021 1
38 33746516 Evaluating the Impact of CYP3A5 Genotype on Post-Transplant Healthcare Resource Utilization in Pediatric Renal and Heart Transplant Recipients Receiving Tacrolimus. 2021 5
39 33751414 Clinical Impact of the Adaptation of Initial Tacrolimus Dosing to the CYP3A5 Genotype After Kidney Transplantation: Systematic Review and Meta-Analysis of Randomized Controlled Trials. 2021 Jul 1
40 33768546 Population pharmacokinetic analysis and dosing guidelines for tacrolimus co-administration with Wuzhi capsule in Chinese renal transplant recipients. 2021 Aug 6
41 33866281 CYP3A5*3 polymorphism and age affect tacrolimus blood trough concentration in myasthenia gravis patients. 2021 Jun 15 2
42 33920149 Relationship between CYP3A5 Polymorphism and Tacrolimus Blood Concentration Changes in Allogeneic Hematopoietic Stem Cell Transplant Recipients during Continuous Infusion. 2021 Apr 10 6
43 33967795 CYP3A5 and UGT1A9 Polymorphisms Influence Immunosuppressive Therapy in Pediatric Kidney Transplant Recipients. 2021 1
44 34058078 Association of CYP3A5 polymorphisms and parathyroid hormone with blood level of tacrolimus in patients with end-stage renal disease. 2021 Sep 4
45 34129685 Impact of CYP3A5 phenotype on tacrolimus time in therapeutic range and clinical outcomes in pediatric renal and heart transplant recipients. 2021 Aug 1
46 34290611 CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients. 2021 6
47 34342024 Effects and safety evaluation of Wuzhi Capsules combined with tacrolimus for the treatment of kidney transplantation recipients. 2021 Dec 1
48 34352707 Blood concentrations of tacrolimus upon conversion from rabeprazole to vonoprazan in renal transplant recipients: Correlation with cytochrome P450 gene polymorphisms. 2021 Oct 1
49 34525930 Effects of CPY3A5 Genetic Polymorphisms on the Pharmacokinetics of Extendedrelease and Immediate-release Tacrolimus Formulations in Renal Transplant Recipients: A Systematic Review and Meta-analysis. 2021 1
50 34620272 Tacrolimus and herbs interactions: a review. 2021 Oct 1 1