Title : CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients.

Pub. Date : 2021 Jun

PMID : 33398393






2 Functional Relationships(s)
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1 CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 This study is aimed at assessing the impact of allelic variants of CYP3A5 and PPARA genes on the pharmacokinetics (PK) of TAC in Brazilian kidney transplant recipients in the first-year post-transplant. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens