Title : The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose-corrected trough concentration in the early period after liver transplantation.

Pub. Date : 2021 Jun

PMID : 33386894






2 Functional Relationships(s)
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1 RESULTS: The combined analysis of donor and recipient CYP3A5 rs776746 could distinguish the metabolic phenotype of tacrolimus into three groups: fast elimination (FE), intermediate elimination (IE), and slow elimination (SE), which was entitled the FIS classification system. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 The combined analysis of donor and recipient CYP3A5 rs776746, recipient SLCO1B1 rs2291075 genotypes, could be helpful to guide the personalized administration of tacrolimus in early period after liver transplantation. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens