Title : Effect of hepar-protecting Wuzhi capsule on Pharmacokinetics and Dose-effect Character of Tacrolimus in Healthy Volunteers.

Pub. Date : 2022 Feb 18

PMID : 35180322






3 Functional Relationships(s)
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1 We elucidate the influence of CYP3A5 and MDR1 genetic polymorphisms on the WZC dose by maintaining Ctrough of TAC in Chinese healthy volunteers. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 The plasma TAC level in volunteers with high CYP3A5 expression was greatly lower than that in those with mutant CYP3A5. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens
3 The plasma TAC level in volunteers with high CYP3A5 expression was greatly lower than that in those with mutant CYP3A5. Tacrolimus cytochrome P450 family 3 subfamily A member 5 Homo sapiens