Pub. Date : 2022 Feb
PMID : 35103348
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The novel CYP3A5*3*6*7 metabolic composite was the significant covariate accounting for 15%-19% of tacrolimus variability in dose (p = 0.002); AUC0-12 h * (p < 0.001), and Cl (p < 0.001). | Tacrolimus | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 2 | CONCLUSIONS: Tacrolimus pharmacokinetics and adverse effects were different among stable kidney transplant recipient groups based upon race and sex with interpatient variability associated with the CYP3A5*3*6*7 metabolic composite. | Tacrolimus | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |