Pub. Date : 2022 Feb 24
PMID : 35202484
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genetic variation within the CYP3A5 gene locus impacts the metabolism of several clinically important drugs, including the immunosuppressants tacrolimus, sirolimus, cyclosporine, and the benzodiazepine midazolam. | Tacrolimus | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 2 | Variable CYP3A5 activity is of clinical importance regarding tacrolimus metabolism. | Tacrolimus | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |