Paclitaxel

tumor protein p53 ; Homo sapiens







240 Article(s)
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1 35058503 RBL2/DREAM-mediated repression of the Aurora kinase A/B pathway determines therapy responsiveness and outcome in p53 WT NSCLC. 2022 Jan 20 1
2 35419287 Propofol Inhibits Proliferation and Augments the Anti-Tumor Effect of Doxorubicin and Paclitaxel Partly Through Promoting Ferroptosis in Triple-Negative Breast Cancer Cells. 2022 1
3 35566044 Anticancer Efficacy of 6-Gingerol with Paclitaxel against Wild Type of Human Breast Adenocarcinoma. 2022 Apr 22 1
4 33002289 Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF-7 human breast cancer cell line. 2021 Feb 1
5 33650658 Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation. 2021 Mar 2
6 33771522 MiR-221-3p-mediated downregulation of MDM2 reverses the paclitaxel resistance of non-small cell lung cancer in vitro and in vivo. 2021 May 15 3
7 34080040 Molecular predictors of the outcome of paclitaxel plus carboplatin neoadjuvant therapy in high-grade serous ovarian cancer patients. 2021 Sep 1
8 34452218 Development of Tailor-Made Dendrimer Ternary Complexes for Drug/Gene Co-Delivery in Cancer. 2021 Aug 13 1
9 34608124 Severe cellular stress activates apoptosis independently of p53 in osteosarcoma. 2021 Oct 4 1
10 34660779 Synergistic Antiproliferative Effects of All-Trans Retinoic Acid and Paclitaxel on Autosomal Dominant Polycystic Kidney Disease Epithelial Cells. 2021 1
11 34799910 P1-39: Paclitaxel induces growth inhibition in gefitinib-resistant PC9-MET cells by downregulating MDM2 and activating p53. 2021 Nov 1
12 34834551 Bioinformatics Analysis Identifies Precision Treatment with Paclitaxel for Hepatocellular Carcinoma Patients Harboring Mutant TP53 or Wild-Type CTNNB1 Gene. 2021 Nov 13 3
13 31648639 Functionalization of Silver Nanoparticles Loaded with Paclitaxel-induced A549 Cells Apoptosis Through ROS-Mediated Signaling Pathways 2020 1
14 32237067 PBK attenuates paclitaxel-induced autophagic cell death by suppressing p53 in H460 non-small-cell lung cancer cells. 2020 May 6
15 32238452 Duloxetine Attenuates Paclitaxel-Induced Peripheral Nerve Injury by Inhibiting p53-Related Pathways. 2020 Jun 1
16 32401925 Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway. 2020 1
17 32632453 Long non-coding RNA LINC-PINT attenuates paclitaxel resistance in triple-negative breast cancer cells via targeting the RNA-binding protein NONO. 2020 Aug 5 2
18 32722340 TP53 Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy. 2020 Jul 24 2
19 33072537 Restoring of miR-193a-5p Sensitizes Breast Cancer Cells to Paclitaxel through P53 Pathway. 2020 Sep 2
20 33363381 UBE2N Regulates Paclitaxel Sensitivity of Ovarian Cancer via Fos/P53 Axis. 2020 3
21 30592172 Paclitaxel Induce Apoptosis of Giant Cells Tumor of Bone via TP53INP1 Signaling. 2019 Feb 3
22 30628717 Introduction of exogenous wild‑type p53 mediates the regulation of oncoprotein 18/stathmin signaling via nuclear factor‑κB in non‑small cell lung cancer NCI‑H1299 cells. 2019 Mar 1
23 31068300 [Silencing RRM1 gene reverses paclitaxel resistance in human breast cancer cell line MCF- 7/R by inducing cell apoptosis]. 2019 Mar 30 1
24 31088908 HIF Inactivation of p53 in Ovarian Cancer Can Be Reversed by Topotecan, Restoring Cisplatin and Paclitaxel Sensitivity. 2019 Aug 1
25 31171918 Effect of Gallic acid in potentiating chemotherapeutic effect of Paclitaxel in HeLa cervical cancer cells. 2019 1
26 31379992 The p53 Modulated Cytotoxicity of Ophiocoma scolopendrina Polysaccharide Against Resistance Ovarian Cancer Cells. 2019 Jul-Sep 1
27 31391192 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers. 2019 Sep 15 1
28 31452796 Shikonin potentiates paclitaxel antitumor efficacy in esophageal cancer cells via the apoptotic pathway. 2019 Sep 1
29 31783991 Topological properties and in vitro identification of essential nodes of the Paclitaxel and Vincristine interactomes in PC-3 cells. 2019 Oct 3
30 31819616 Low-Concentration PTX And RSL3 Inhibits Tumor Cell Growth Synergistically By Inducing Ferroptosis In Mutant p53 Hypopharyngeal Squamous Carcinoma. 2019 3
31 28884602 Enhancement of anticancer activity by silibinin and paclitaxel combination on the ovarian cancer. 2018 Nov 1
32 29203914 Synthetically lethal nanoparticles for treatment of endometrial cancer. 2018 Jan 3
33 29334216 Lysosome-Independent Intracellular Drug/Gene Codelivery by Lipoprotein-Derived Nanovector for Synergistic Apoptosis-Inducing Cancer-Targeted Therapy. 2018 Feb 12 1
34 29373839 Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel. 2018 Apr 10 1
35 29684847 The association between p53 protein phosphorylation at serine 15, serine 20 and sensitivity of cells isolated from patients with ovarian cancer and cell lines to chemotherapy in in vitro study. 2018 Jun 3
36 29727353 Role of Survivin and p53 Expression in Response of Primary Culture of Ovarian Cancer Cells to Treatment With Chemotherapeutic Agents. 2018 Jul 1
37 29980405 Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals. 2018 Aug 1
38 30173893 Paclitaxel promotes lung cancer cell apoptosis via MEG3-P53 pathway activation. 2018 Sep 26 3
39 28522974 Low-Dose Paclitaxel Inhibits Tumor Cell Growth by Regulating Glutaminolysis in Colorectal Carcinoma Cells. 2017 1
40 28869866 Synergistic antitumor effect mediated by a paclitaxel-conjugated polymeric micelle-coated oncolytic adenovirus. 2017 Nov 1
41 26696550 TP53 Codon 72 Polymorphism Predicts Efficacy of Paclitaxel Plus Capecitabine Chemotherapy in Advanced Gastric Cancer Patients. 2016 Jan 4
42 26773176 The role of Six1 signaling in paclitaxel-dependent apoptosis in MCF-7 cell line. 2016 Jan 1 1
43 26799187 p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells. 2016 Feb 16 3
44 27191893 Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations. 2016 Jul 26 1
45 27304668 Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways. 2016 Jul 5 2
46 27431785 Synergistic Anti-glioma Effects in Vitro and in Vivo of Enediyne Antibiotic Neocarzinostatin and Paclitaxel via Enhanced Growth Delay and Apoptosis-Induction. 2016 Oct 1 1
47 27764550 Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53. 2016 Dec 1
48 27779649 Effect of curcumin and paclitaxel on breast carcinogenesis. 2016 Dec 2
49 27994465 Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis. 2016 1
50 25164962 The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cells. 2015 Jan 1