Title : Effect of curcumin and paclitaxel on breast carcinogenesis.

Pub. Date : 2016 Dec

PMID : 27779649






2 Functional Relationships(s)
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1 Results indicated that curcumin combined with paclitaxel decreased c-Ha-Ras, Rho-A, p53 and Bcl-xL gene expression in comparison to control and substances alone in MCF-7 cell line. Paclitaxel tumor protein p53 Homo sapiens
2 Curcumin alone and combined with paclitaxel increased p53, Bid, caspase-3, caspase-8 and Bax gene expression in MDA-MB-231, whereas Bcl-xL decreased such expression in MDA-MB-231 cells. Paclitaxel tumor protein p53 Homo sapiens