Paclitaxel

tumor protein p53 ; Homo sapiens







240 Article(s)
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201 11099323 p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma. 2000 Dec 1 3
202 11129289 Development and validation of sensitive assays to quantitate gene expression after p53 gene therapy and paclitaxel chemotherapy using in vivo dosing in tumor xenograft models. 2000 Nov 1
203 11175336 Formation of nuclear Bax/p53 complexes is associated with chemotherapy induced apoptosis. 2000 Dec 14 1
204 11205220 p53 status is neither a predictive nor a prognostic variable in patients with advanced ovarian cancer treated with a paclitaxel-based regimen. 2000 Nov-Dec 2
205 11899648 A study of the value of p53, HER2, and Bcl-2 in the prediction of response to doxorubicin and paclitaxel as single agents in metastatic breast cancer: a companion study to EORTC 10923. 2000 Oct 1
206 10210535 Role of p53 and p16 gene alterations in determining response to concurrent paclitaxel and radiation in solid tumor. 1999 Apr 2
207 10210540 Paclitaxel and concurrent radiation therapy for locally advanced adenocarcinomas of the pancreas, stomach, and gastroesophageal junction. 1999 Apr 1
208 10347252 Overexpression of p21(waf1) decreases G2-M arrest and apoptosis induced by paclitaxel in human sarcoma cells lacking both p53 and functional Rb protein. 1999 Jun 1
209 10421546 Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation. 1999 Jul 15 7
210 10424768 Sequence-dependent antagonism between fluorouracil and paclitaxel in human breast cancer cells. 1999 Aug 1 1
211 10446979 DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4. 1999 Aug 1 1
212 10453723 Failure of taxol-based combination chemotherapy for malignant glioma cannot be overcome by G2/M checkpoint abrogators or altering the p53 status. 1999 2
213 10471519 Molecular effects of paclitaxel: myths and reality (a critical review). 1999 Oct 8 2
214 10534572 Molecular effects of taxol and caffeine on pancreatic cancer cells. 1999 Nov 1
215 10554637 Radiochemotherapy with paclitaxel: synchronization effects and the role of p53. 1999 Oct 1
216 10665656 Cisplatin-resistant HeLa cells are resistant to apoptosis via p53-dependent and -independent pathways. 1999 Dec 1
217 10697517 Effect of paclitaxel pretreatment on radiation-induced p53-dependent apoptosis. 1999 Nov-Dec 3
218 9472635 Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells: association with bcl-2 phosphorylation but neither activation of p53 nor G2/M cell cycle arrest. 1998 2
219 9563876 Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer. 1998 Apr 3
220 9563901 Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment. 1998 Apr 3
221 9584207 Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53. 1998 May 4
222 9633517 Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis. 1998 May 25 5
223 9636834 Ovarian cancer cisplatin-resistant cell lines: multiple changes including collateral sensitivity to Taxol. 1998 Apr 6
224 9661042 Evidence of p53-induced apoptosis in cancer cells exposed to taxol. 1998 Jun 1
225 9703286 Therapy effect of either paclitaxel or cyclophosphamide combination treatment in patients with epithelial ovarian cancer and relation to TP53 gene status. 1998 Aug 2
226 9772293 Cell cycle arrest in ovarian cancer cell lines does not depend on p53 status upon treatment with cytostatic drugs. 1998 Nov 3
227 9792903 Paclitaxel and concurrent radiation for locally advanced pancreatic carcinoma. 1998 Nov 1 1
228 9865905 Relationship between paclitaxel activity and pathobiology of human solid tumors. 1998 Dec 2
229 9865921 CDK4 down-regulation induced by paclitaxel is associated with G1 arrest in gastric cancer cells. 1998 Dec 1
230 9041188 p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel. 1997 Mar 1 3
231 9108094 Synergy of Taxol and radioimmunotherapy with yttrium-90-labeled chimeric L6 antibody: efficacy and toxicity in breast cancer xenografts. 1997 Apr 15 3
232 9206986 Weekly paclitaxel as a radiation sensitizer for locally advanced gastric and pancreatic cancers: the Brown University Oncology Group experience. 1997 May 1 1
233 9815592 Adenovirus E1A expression enhances the sensitivity of an ovarian cancer cell line to multiple cytotoxic agents through an apoptotic mechanism. 1997 Nov 1
234 8564846 Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis. 1996 Jan 4
235 8763853 The interaction of taxol and vinblastine with radiation induction of p53 and p21 WAF1/CIP1. 1996 Jul 3
236 8826941 p53 mutations do not predict response to paclitaxel/radiation for nonsmall cell lung carcinoma. 1996 Sep 15 3
237 8943066 BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway. 1996 Nov 26 1
238 7553639 Taxol induction of p21WAF1 and p53 requires c-raf-1. 1995 Oct 15 9
239 8521300 LPS and Taxol activate Lyn kinase autophosphorylation in Lps(n), but not in Lpsd), macrophages. 1995 May 1
240 8521385 Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53. 1995 Dec 15 3