Title : The role of Six1 signaling in paclitaxel-dependent apoptosis in MCF-7 cell line.

Pub. Date : 2016 Jan 1

PMID : 26773176






1 Functional Relationships(s)
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1 In paclitaxel-resistant cells, there was a significant increase in Six1 and BCL-2 mRNA levels (p = 0.0007) with a marked decrease in pro-apoptotic Bax mRNA expression level (p = 0.03); however, there was no significant change in P53 expression (p = 0.025). Paclitaxel tumor protein p53 Homo sapiens