Pub. Date : 2018 Jan
PMID : 29203914
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our objective was to engender synthetic lethality to paclitaxel (PTX), the frontline treatment for endometrial cancer, in tumours with mutant p53 and enhance the therapeutic efficacy using polymeric nanoparticles (NPs). | Paclitaxel | tumor protein p53 | Homo sapiens |
| 2 | Our objective was to engender synthetic lethality to paclitaxel (PTX), the frontline treatment for endometrial cancer, in tumours with mutant p53 and enhance the therapeutic efficacy using polymeric nanoparticles (NPs). | Paclitaxel | tumor protein p53 | Homo sapiens |
| 3 | Together, our data provide compelling evidence for future studies of BIBF- and PTX-loaded NPs as a therapeutic opportunity for LOF p53 cancers. | Paclitaxel | tumor protein p53 | Homo sapiens |