Pub. Date : 2021 May 15
PMID : 33771522
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PTX increased miR-221-3p expression and regulated MDM2/P53 expression in the PTX-sensitive NSCLC strain (A549). | Paclitaxel | tumor protein p53 | Homo sapiens |
2 | PTX increased miR-221-3p expression and regulated MDM2/P53 expression in the PTX-sensitive NSCLC strain (A549). | Paclitaxel | tumor protein p53 | Homo sapiens |
3 | In conclusion, miR-221-3p overexpression could regulate MDM2/p53 signaling pathway to reverse the PTX resistance of NSCLC and induce apoptosis in vitro and vivo. | Paclitaxel | tumor protein p53 | Homo sapiens |