Pub. Date : 2015 Jan
PMID : 25164962
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sequential treatment of Taxol or cisplatin, followed by MK-2206, induced a synergistic inhibition of cell proliferation and effectively promoted cell death, either by inhibiting the phosphorylation of Akt and its downstream effectors 4E-BP1 and p70S6K in SKOV3 cells or by restoring p53 levels, which were downregulated after Taxol or cisplatin treatment, in ES2 cells. | Paclitaxel | tumor protein p53 | Homo sapiens |