Threonine

cyclin dependent kinase 2 ; Homo sapiens







111 Article(s)
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51 15824106 Novel role for cyclin-dependent kinase 2 in neuregulin-induced acetylcholine receptor epsilon subunit expression in differentiated myotubes. 2005 Jun 10 4
52 15855168 Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase. 2005 Jun 17 1
53 15941859 Catalytic activities of G1 cyclin-dependent kinases and phosphorylation of retinoblastoma protein in mobilized peripheral blood CD34+ hematopoietic progenitor cells. 2005 Aug 2
54 16082227 Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A. 2005 Sep 1
55 16107892 CDK2 catalytic activity and loss of nuclear tethering of retinoblastoma protein in childhood acute lymphoblastic leukemia. 2005 Oct 1
56 16191191 Biochemical characterization of Cdk2-Speedy/Ringo A2. 2005 Sep 28 2
57 16706194 [E1A oncogene effect on the ability of p21(Waf1) to regulate G1/S arrest in E1A-expressing transformants following irradiation]. 2005 2
58 14597612 p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells. 2004 Feb 6 4
59 15011833 Adenovirus expressing mutant p27kip1 enhanced apoptosis against cholangiocarcinoma than adenovirus-p27kip1 wild type. 2004 Jan-Feb 1
60 15122251 Bioluminescent imaging of Cdk2 inhibition in vivo. 2004 Jun 1
61 15355984 Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes. 2004 Nov 12 4
62 15475007 P27 expression is regulated by separate signaling pathways, downstream of Ras, in each cell cycle phase. 2004 Nov 1 1
63 12475985 Inhibition of cdk2 activating phosphorylation by mevastatin. 2003 Feb 14 4
64 12676926 Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73. 2003 Jul 25 1
65 12745075 Abolishment of the interaction between cyclin-dependent kinase 2 and Cdk-associated protein phosphatase by a truncated KAP mutant. 2003 May 30 1
66 14551212 Phosphorylations of cyclin-dependent kinase 2 revisited using two-dimensional gel electrophoresis. 2003 Dec 26 1
67 14646596 Biochemical characterizations reveal different properties between CDK4/cyclin D1 and CDK2/cyclin A. 2003 Oct 31 1
68 11959850 Kinetic mechanism of activation of the Cdk2/cyclin A complex. Key role of the C-lobe of the Cdk. 2002 Jun 28 1
69 12359725 Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2. 2002 Dec 6 10
70 12417722 Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. 2002 Dec 1
71 12485874 Activation and phosphorylation on Thr-160 of nuclear-targeted CDK2 Is ERK dependent. 2002 Nov 1
72 12490153 Cyclin D-cdk6 complex is targeted by p21(WAF) in growth-arrested lymphoma cells. 2002 Oct-Dec 1
73 11029468 Kinetic basis for activation of CDK2/cyclin A by phosphorylation. 2001 Jan 5 2
74 11113184 Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop. 2001 Jan 2
75 11238922 HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression. 2001 Mar 2
76 11264176 Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function. 2001 Apr 1 2
77 11278991 Specific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication. 2001 Jun 15 4
78 11463845 Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. 2001 Aug 2
79 11504716 Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle. 2001 Nov 2 1
80 11676600 Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells. 2001 Nov 2
81 10652300 Degradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2. 2000 Feb 4 1
82 10846177 Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks. 2000 Sep 15 2
83 10866826 Analysis of CAK activities from human cells. 2000 Jul 2
84 10931829 The effects of changing the site of activating phosphorylation in CDK2 from threonine to serine. 2000 Oct 20 5
85 10987270 Aberrant transcripts of the cyclin-dependent kinase-associated protein phosphatase in hepatocellular carcinoma. 2000 Sep 1 1
86 9989807 A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2. 1999 Jan 21 2
87 10085115 Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity. 1999 Mar 26 1
88 10432313 Lyn is activated during late G1 of stem-cell-factor-induced cell cycle progression in haemopoietic cells. 1999 Aug 15 1
89 10511310 Loss of cell cycle control by deregulation of cyclin-dependent kinase 2 kinase activity in Evi-1 transformed fibroblasts. 1999 Sep 2
90 10559988 The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. 1999 Nov 2
91 10611320 Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity. 1999 Dec 21 1
92 9521129 Purification and crystallization of the CDK-associated protein phosphatase KAP expressed in Escherichia coli. 1998 Feb 1
93 9560221 A distinct cyclin-dependent kinase-activating kinase of Arabidopsis thaliana. 1998 Apr 28 2
94 9725911 Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities. 1998 Sep 1
95 10036778 A rice homolog of Cdk7/MO15 phosphorylates both cyclin-dependent protein kinases and the carboxy-terminal domain of RNA polymerase II. 1998 Dec 1
96 9099745 Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2. 1997 Apr 18 3
97 9139732 Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases. 1997 May 9 3
98 9141623 Translocation of cdk2 to the nucleus during G1-phase in PDGF-stimulated human fibroblasts. 1997 Apr 10 1
99 9388487 Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2. 1997 Nov 17 1
100 9399644 Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes. 1997 Nov 20 2