Title : Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle.

Pub. Date : 2001 Nov 2

PMID : 11504716






1 Functional Relationships(s)
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1 We determined one site of phosphorylation by cyclin A-CDK2 at the C terminus of MEF, using mass-spectrometry; mutation of three serine or threonine residues in this region significantly reduced phosphorylation of MEF by cyclin A and reduced cyclin A-mediated suppression of its transactivating activity. Threonine cyclin dependent kinase 2 Homo sapiens