Title : CDK2 catalytic activity and loss of nuclear tethering of retinoblastoma protein in childhood acute lymphoblastic leukemia.

Pub. Date : 2005 Oct

PMID : 16107892






1 Functional Relationships(s)
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1 Together with the immunocytochemical analysis at a single cell level that Rb was phosphorylated at serine 612 and threonine 821, sites known to be phosphorylated by CDK2, the data indicated the presence of CDK2 catalytic activity and loss of Rb"s nuclear affinity in ALL cells. Threonine cyclin dependent kinase 2 Homo sapiens