Title : Loss of cell cycle control by deregulation of cyclin-dependent kinase 2 kinase activity in Evi-1 transformed fibroblasts.

Pub. Date : 1999 Sep

PMID : 10511310






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We show that the elevated cyclin A-Cdk2 activity is due to the combination of increased accumulation and stabilization of cyclin A bound to a faster-migrating species of Cdk2 believed to be the active threonine 160 phosphorylated form and a substantial reduction in complexed p27. Threonine cyclin dependent kinase 2 Homo sapiens
2 We show that the elevated cyclin A-Cdk2 activity is due to the combination of increased accumulation and stabilization of cyclin A bound to a faster-migrating species of Cdk2 believed to be the active threonine 160 phosphorylated form and a substantial reduction in complexed p27. Threonine cyclin dependent kinase 2 Homo sapiens