Pub. Date : 2004 Feb 6
PMID : 14597612
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cyclin-dependent kinase (CDK)-activating kinase (CAK) phosphorylates a conserved threonine residue on CDKs and activates them. | Threonine | cyclin dependent kinase 2 | Homo sapiens |
| 2 | p42 is essential for the phosphorylation of Thr-160 and activation of CDK2. | Threonine | cyclin dependent kinase 2 | Homo sapiens |
| 3 | A dominant-negative p42 mutant, T161A, and posttranscriptional gene silencing of p42 with RNA(i)-impaired Thr-160 phosphorylation and activity of CDK2. | Threonine | cyclin dependent kinase 2 | Homo sapiens |
| 4 | Purified p42 phosphorylated glutathione S-transferase-CDK2 at Thr-160 within the T-loop and activated its histone H1 kinase activity. | Threonine | cyclin dependent kinase 2 | Homo sapiens |