Histidine

amyloid beta precursor protein ; Homo sapiens







74 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35216047 Mechanistic Insights into the Polymorphic Associations and Cross-Seeding of Aβ and hIAPP in the Presence of Histidine Tautomerism: An All-Atom Molecular Dynamic Study. 2022 Feb 9 1
2 34163842 Modification of amyloid-beta peptide aggregation via photoactivation of strained Ru(ii) polypyridyl complexes. 2021 Apr 24 1
3 34343891 Structural significance of Neprylysin from Streptococcus suis GZ1 in the degradation of Aβ peptides, a causative agent in Alzheimer's disease. 2021 Sep 1
4 34371051 Amino acid-functionalized chitosan beads for in vitro copper ions uptake in the presence of histidine. 2021 Oct 1 4
5 34878265 Tuning Receptor Properties of Metal-Amyloid Beta Complexes. Studies on the Interaction between Ni(II)-Aβ5-9 and Phosphates/Nucleotides. 2021 Dec 20 1
6 31630339 Copper Ion Uptake by Chitosan in the Presence of Amyloid-β and Histidine. 2020 Mar 2
7 32255544 Copper(II) partially protects three histidine residues and the N-terminus of amyloid-β peptide from diethyl pyrocarbonate (DEPC) modification. 2020 Jun 1
8 32551634 Impact of A2V Mutation and Histidine Tautomerism on Aβ42 Monomer Structures from Atomistic Simulations. 2020 Jul 27 1
9 32567070 Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers? 2020 Aug 1
10 32630528 The English (H6R) Mutation of the Alzheimer's Disease Amyloid-β Peptide Modulates Its Zinc-Induced Aggregation. 2020 Jun 25 2
11 32730791 Tautomeric Effect of Histidine on β-Sheet Formation of Amyloid Beta 1-40: 2D-IR Simulations. 2020 Aug 18 1
12 33052996 On the propagation of the OH radical produced by Cu-amyloid beta peptide model complexes. Insight from molecular modelling. 2020 Nov 1 1
13 30694660 Alanine Scanning Effects on the Biochemical and Biophysical Properties of Intrinsically Disordered Proteins: A Case Study of the Histidine to Alanine Mutations in Amyloid-β42. 2019 Feb 25 2
14 30771375 Intrinsic origin of amyloid aggregation: Behavior of histidine (εεε) and (δδδ) tautomer homodimers of Aβ (1-40). 2019 May 2
15 30813720 Tautomerization Effect of Histidines on Oligomer Aggregation of β-Amyloid(1-40/42) during the Early Stage: Tautomerism Hypothesis for Misfolding Protein Aggregation. 2019 May 15 1
16 31013069 X-ray Absorption Spectroscopy Investigations of Copper(II) Coordination in the Human Amyloid β Peptide. 2019 May 6 1
17 31658742 Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies. 2019 Oct 10 1
18 29215101 Evaluation of Cu(i) binding to the E2 domain of the amyloid precursor protein - a lesson in quantification of metal binding to proteins via ligand competition. 2018 Jan 24 1
19 28096459 Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production. 2017 Mar 3 4
20 28682389 Copper induced spin state change of heme-Aβ associated with Alzheimer's disease. 2017 Oct 10 2
21 28910862 Effects of Newly Synthesized Recombinant Human Amyloid-β Complexes and Poly-Amyloid-β Fibers on Cell Apoptosis and Cognitive Decline. 2017 Nov 28 1
22 27687728 Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence. 2016 Nov 11 1
23 25171714 The histidine composition of the amyloid-β domain, but not the E1 copper binding domain, modulates β-secretase processing of amyloid-β protein precursor in Alzheimer's disease. 2015 5
24 25211009 Key roles for tyrosine 10 in aβ-heme complexes and its relevance to oxidative stress. 2015 Mar 16 2
25 25597800 Development of gold nanoparticle based colorimetric method for quantitatively studying the inhibitors of Cu(2+)/Zn(2+) induced β-amyloid peptide assembly. 2015 Feb 9 1
26 25969353 A novel method for expression and purification of authentic amyloid-β with and without (15)N labels. 2015 Sep 1
27 26118700 An improved method for high-level soluble expression and purification of recombinant amyloid-beta peptide for in vitro studies. 2015 Oct 1
28 26252621 Alzheimer's Disease: A Heme-Aβ Perspective. 2015 Sep 15 1
29 24523414 Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle. 2014 Apr 4 2
30 24595206 Transition-metal-substituted polyoxometalate derivatives as functional anti-amyloid agents for Alzheimer's disease. 2014 Mar 4 1
31 24803226 Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer's disease. 2014 1
32 24858299 The protease activity of transthyretin reverses the effect of pH on the amyloid-β protein/heparan sulfate proteoglycan interaction: a biochromatographic study. 2014 Aug 1
33 25140899 Deciphering the glycolipid code of Alzheimer's and Parkinson's amyloid proteins allowed the creation of a universal ganglioside-binding peptide. 2014 2
34 25193696 Key roles of Arg(5), Tyr(10) and his residues in Aβ-heme peroxidase: relevance to Alzheimer's disease. 2014 Sep 26 5
35 23289528 Aβ interacts with both the iron center and the porphyrin ring of heme: mechanism of heme's action on Aβ aggregation and disaggregation. 2013 Feb 18 2
36 23609990 Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide. 2013 Oct 1
37 24037720 Characterization of the polymorphic states of copper(II)-bound Aβ(1-16) peptides by computational simulations. 2013 Nov 5 3
38 24274576 Investigation of Cu2+ binding to human and rat amyloid fragments Aβ (1-16) with a protein nanopore. 2013 Dec 17 1
39 22558227 Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies. 2012 2
40 20842634 His-tag binding by antibody C706 mimics β-amyloid recognition. 2011 Jul-Aug 2
41 21341665 Molecular-level examination of Cu2+ binding structure for amyloid fibrils of 40-residue Alzheimer's β by solid-state NMR spectroscopy. 2011 Mar 16 2
42 21445432 Computational calculations of pKa values of imidazole in Cu(II) complexes of biological relevance. 2011 May 7 1
43 21491887 Substantial contribution of the two imidazole rings of the His13-His14 dyad to Cu(II) binding in amyloid-β(1-16) at physiological pH and its significance. 2011 Sep 1 1
44 19685013 Copper enhances amyloid-beta peptide neurotoxicity and non beta-aggregation: a series of experiments conducted upon copper-bound and copper-free amyloid-beta peptide. 2010 May 2
45 20061603 Histidine 14 modulates membrane binding and neurotoxicity of the Alzheimer's disease amyloid-beta peptide. 2010 1
46 20371992 [Conformational regulation of amyloid beta-peptide by lipid membranes and metal ions]. 2010 Apr 1
47 21187975 The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β. 2010 Dec 20 4
48 19338344 Copper(II) binding to amyloid-beta fibrils of Alzheimer's disease reveals a picomolar affinity: stoichiometry and coordination geometry are independent of Abeta oligomeric form. 2009 May 26 1
49 19780898 Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein. 2009 Dec 1
50 18599641 The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease. 2008 Oct 1