Title : Tuning Receptor Properties of Metal-Amyloid Beta Complexes. Studies on the Interaction between Ni(II)-Aβ5-9 and Phosphates/Nucleotides.

Pub. Date : 2021 Dec 20

PMID : 34878265

1 Functional Relationships(s)
Compound Name
Protein Name
1 In this work, we found that a N-truncated Abeta analogue bearing a His-2 motif, Abeta5-9, forms a stable Ni(II) high-spin octahedral complex at a physiological pH of 7.4 with labile coordination sites and facilitates ternary interactions with phosphates and nucleotides. Histidine amyloid beta precursor protein Homo sapiens