Title : Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle.

Pub. Date : 2014 Apr 4

PMID : 24523414






2 Functional Relationships(s)
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Protein Name
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1 Both (13)C and (15)N SSNMR results show that Cu(+) coordinates to Abeta(1-40) fibrils primarily through the side chain Ndelta of both His-13 and His-14, suggesting major rearrangements from the Cu(2+) coordination via Nepsilon in the redox cycle. Histidine amyloid beta precursor protein Homo sapiens
2 Both (13)C and (15)N SSNMR results show that Cu(+) coordinates to Abeta(1-40) fibrils primarily through the side chain Ndelta of both His-13 and His-14, suggesting major rearrangements from the Cu(2+) coordination via Nepsilon in the redox cycle. Histidine amyloid beta precursor protein Homo sapiens