Title : Copper(II) binding to amyloid-beta fibrils of Alzheimer's disease reveals a picomolar affinity: stoichiometry and coordination geometry are independent of Abeta oligomeric form.

Pub. Date : 2009 May 26

PMID : 19338344

1 Functional Relationships(s)
Compound Name
Protein Name
1 Electron paramagnetic resonance studies (EPR) with Abeta His/Ala analogues suggest a dynamic view of the tetragonal Cu(2+) complex, with axial as well as equatorial coordination of imidazole nitrogens creating an ensemble of coordination geometries in exchange between each other. Histidine amyloid beta precursor protein Homo sapiens