Title : Transition-metal-substituted polyoxometalate derivatives as functional anti-amyloid agents for Alzheimer's disease.

Pub. Date : 2014 Mar 4

PMID : 24595206






1 Functional Relationships(s)
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1 Here we show that our designed series of transition metal-functionalized POM derivatives with a defined histidine-chelated binding site have much better Abeta inhibition and peroxidase-like activity inhibition effects than the parent POM. Histidine amyloid beta precursor protein Homo sapiens