PML nuclear body scaffold ; Homo sapiens






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51 8819070 Variant and masked translocations in acute promyelocytic leukemia. Leuk Lymphoma 1996 Jul 4
52 8826895 Successful treatment of acute promyelocytic leukaemia with all-trans-retinoic-acid during late pregnancy. Br J Haematol 1996 Sep 4
53 8839862 Alterations in expression, binding to ligand and DNA, and transcriptional activity of rearranged and wild-type retinoid receptors in retinoid-resistant acute promyelocytic leukemia cell lines. Blood 1996 Oct 1 2
54 8874178 The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells. Blood 1996 Oct 15 3
55 8881287 [Effect of PML and PML-RAR on the transactivation properties and subcellular localization of steroid hormone receptors]. Ann Endocrinol (Paris) 1996 3
56 8916959 Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line. Blood 1996 Nov 15 2
57 8952536 Heterogeneous nuclear expression of the promyelocytic leukemia (PML) protein in normal and neoplastic human tissues. Am J Pathol 1996 Dec 1
58 8956873 Acute promyelocytic leukemia with t(15;16;17;19) and unusual fluorescence in situ hybridization pattern with PML and RARA probes. Cancer Genet Cytogenet 1996 Nov 1
59 8986606 The PML and PML/RARalpha domains: from autoimmunity to molecular oncology and from retinoic acid to arsenic. Exp Cell Res 1996 Dec 15 8
60 9016654 Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1. Nucleic Acids Res 1996 Dec 15 2
61 9089745 Cutaneous infiltration by leukemic cells in acute promyelocytic leukemia of a child after treatment with all-trans retinoic acid. Pediatr Hematol Oncol 1997 Mar-Apr 2
62 9103677 Characterisation of the PML/RAR alpha rearrangement associated with t(15;17) acute promyelocytic leukaemia. Curr Top Microbiol Immunol 1997 1
63 9108090 Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia. Proc Natl Acad Sci U S A 1997 Apr 15 9
64 9129042 Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 1997 May 1 4
65 9192750 A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation. Blood 1997 Jun 15 4
66 9209367 Molecular analysis of the t(15;17) translocation in de novo and secondary acute promyelocytic leukemia. Leukemia 1997 Apr 2
67 9234742 Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling. Mol Cell Biol 1997 Aug 9
68 9242550 Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells. Blood 1997 Aug 1 5
69 9294197 Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies. Proc Natl Acad Sci U S A 1997 Sep 16 1
70 9369431 Mutant AF-2 domain of PML-RARalpha in retinoic acid-resistant NB4 cells: differentiation induced by RA is triggered directly through PML-RARalpha and its down-regulation in acute promyelocytic leukemia. Leukemia 1997 Nov 7
71 9395203 Stable overexpression of PML alters regulation of cell cycle progression in HeLa cells. Carcinogenesis 1997 Nov 1
72 9398618 Cell-cycle regulation of DNA damage-induced expression of the suppressor gene PML. Biochem Biophys Res Commun 1997 Nov 26 2
73 9414089 The promyelocytic leukemia protein PML has a pro-apoptotic activity mediated through its RING domain. FEBS Lett 1997 Nov 24 2
74 9417884 Cystine starvation induces reversible large-body formation from nuclear bodies in T24 cells. Exp Cell Res 1997 Nov 25 5
75 9427741 Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J 1998 Jan 2 2
76 9434633 Transcriptional repression by the promyelocytic leukemia protein, PML. Exp Cell Res 1997 Dec 15 2
77 9450572 Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells. J Natl Cancer Inst 1998 Jan 21 1
78 9452416 Covalent modification of PML by the sentrin family of ubiquitin-like proteins. J Biol Chem 1998 Feb 6 1
79 9460497 Occurrence of a novel t(11;19)(q13;q13.3) in complete remission of acute promyelocytic leukemia. Cancer Genet Cytogenet 1998 Feb 2
80 9486654 Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 1998 Feb 19 2
81 9486655 Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia. Nature 1998 Feb 19 5
82 9531570 Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia. Blood 1998 Apr 15 5
83 9535176 Acute promyelocytic leukemia: cellular and molecular basis of differentiation and apoptosis. Pharmacol Ther 1997 Oct-Dec 5
84 9558392 Constitutive expression of the promyelocytic leukemia-associated oncogene PML-RARalpha in TF1 cells: isoform-specific and retinoic acid-dependent effects on growth, bcl-2 expression, and apoptosis. Blood 1998 May 1 5
85 9576546 Localised 1H-MR spectroscopy for metabolic characterisation of diffuse and focal brain lesions in patients infected with HIV. J Neurol Neurosurg Psychiatry 1998 Apr 3
86 9581846 4-Oxoretinol, a metabolite of retinol in the human promyelocytic leukemia cell line NB4, induces cell growth arrest and granulocytic differentiation. Cancer Res 1998 May 1 1
87 9591778 The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies. Oncogene 1998 Apr 16 1
88 9596679 Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells. Blood 1998 Jun 1 6
89 9624536 In vitro response to all-trans retinoic acid of acute promyelocytic leukemias with nonreciprocal PML/RARA or RARA/PML fusion genes. Genes Chromosomes Cancer 1998 Jul 5
90 9657734 Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia. Blood 1998 Jul 15 2
91 9671405 Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein. Oncogene 1998 Jun 4 1
92 9671411 Cooperation between the RING + B1-B2 and coiled-coil domains of PML is necessary for its effects on cell survival. Oncogene 1998 Jun 4 3
93 9671498 Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML. Mol Cell Biol 1998 Aug 1
94 9694705 Leukemic cellular retinoic acid resistance and missense mutations in the PML-RARalpha fusion gene after relapse of acute promyelocytic leukemia from treatment with all-trans retinoic acid and intensive chemotherapy. Blood 1998 Aug 15 3
95 9716575 Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner. Blood 1998 Sep 1 17
96 9716606 Targeting of PML/RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells. Blood 1998 Sep 1 2
97 9746761 Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein. Blood 1998 Oct 1 10
98 9756909 Identification of three major sentrinization sites in PML. J Biol Chem 1998 Oct 9 2
99 9772451 [Double effects of arsenic trioxide (As2O3) on acute promyelocytic leukemic cell line]. Zhonghua Yi Xue Za Zhi 1997 Jul 4
100 9778041 Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells. Oncogene 1998 Oct 8 2