| 1 |
33831975 | The Effect of Metformin on Male Reproductive Function and Prostate: An Updated Review. | 2022 Jan |
1 |
| 2 |
35072253 | Metformin in selected malignancies in women. | 2022 Jan 24 |
2 |
| 3 |
35125086 | Nimbolide, a Neem Limonoid, Inhibits Angiogenesis in Breast Cancer by Abrogating Aldose Reductase Mediated IGF-1/PI3K/Akt Signalling. | 2022 |
1 |
| 4 |
35142713 | One Bout of Resistance Training Does Not Enhance Metformin Actions in Prediabetic and Diabetic Individuals. | 2022 Jul 1 |
3 |
| 5 |
33227290 | The effect of metformin in EML4-ALK+ lung cancer alone and in combination with crizotinib in cell and rodent models. | 2021 Jan |
1 |
| 6 |
33713207 | The prevalence of secondary neoplasms in acromegalic patients: possible preventive and/or protective role of metformin. | 2021 Jun |
1 |
| 7 |
33884414 | Effects of Behavioral Weight Loss and Metformin on IGFs in Cancer Survivors: A Randomized Trial. | 2021 Sep 27 |
3 |
| 8 |
31816435 | The influence of metformin on IGF-1 levels in humans: A systematic review and meta-analysis. | 2020 Jan |
8 |
| 9 |
32934724 | Therapeutic effect of metformin in the treatment of endometrial cancer. | 2020 Nov |
1 |
| 10 |
31628524 | Metformin plus first-line chemotherapy versus chemotherapy alone in the treatment of epithelial ovarian cancer: a prospective open-label pilot trial. | 2019 Dec |
1 |
| 11 |
31886264 | Role of Metformin on Osteoblast Differentiation in Type 2 Diabetes. | 2019 |
1 |
| 12 |
30147674 | Metformin, an Anti-diabetic Drug to Target Leukemia. | 2018 |
2 |
| 13 |
28196954 | Metformin and thyroid disease. | 2017 Apr |
1 |
| 14 |
28253329 | Metformin inhibits the proliferation of benign prostatic epithelial cells. | 2017 |
2 |
| 15 |
28927103 | Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer. | 2017 Sep |
1 |
| 16 |
29241458 | Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells. | 2017 Dec 14 |
4 |
| 17 |
26902691 | Metformin may protect nondiabetic breast cancer women from metastasis. | 2016 Apr |
2 |
| 18 |
27009398 | Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states. | 2016 Mar 24 |
1 |
| 19 |
27144340 | Metformin restores crizotinib sensitivity in crizotinib-resistant human lung cancer cells through inhibition of IGF1-R signaling pathway. | 2016 Jun 7 |
2 |
| 20 |
27293994 | YAP/TAZ regulates the insulin signaling via IRS1/2 in endometrial cancer. | 2016 |
1 |
| 21 |
27654259 | Insulin-Like Growth Factor 1/Mammalian Target of Rapamycin and AMP-Activated Protein Kinase Signaling Involved in the Effects of Metformin in the Human Endometrial Cancer. | 2016 Nov |
2 |
| 22 |
27745917 | Prospective evaluation of the molecular effects of metformin on the endometrium in women with newly diagnosed endometrial cancer: A window of opportunity study. | 2016 Dec |
1 |
| 23 |
25305450 | Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. | 2015 Jan 28 |
1 |
| 24 |
25640355 | Metformin down-regulates endometrial carcinoma cell secretion of IGF-1 and expression of IGF-1R. | 2015 |
3 |
| 25 |
25687657 | Modulation of the IGF system and proliferation in human endometrial stromal cells by metformin: a dose-dependent effect. | 2015 Aug |
1 |
| 26 |
25862373 | Metformin inhibits the proliferation of human prostate cancer PC-3 cells via the downregulation of insulin-like growth factor 1 receptor. | 2015 May 22 |
2 |
| 27 |
26514337 | Acromegaly presenting with low insulin-like growth factor-1 levels and diabetes: a case report. | 2015 Oct 30 |
1 |
| 28 |
26995937 | Insulin-like growth factor-1 isoforms in human ovary. Preliminary report on the expression of the IGF-1 gene in PCOS patients and healthy controls. | 2015 Dec |
1 |
| 29 |
24437490 | Metformin inhibits androgen-induced IGF-IR up-regulation in prostate cancer cells by disrupting membrane-initiated androgen signaling. | 2014 Apr |
3 |
| 30 |
24603137 | Human granulosa cells: insulin and insulin-like growth factor-1 receptors and aromatase expression modulation by metformin. | 2014 |
1 |
| 31 |
24972190 | Anti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer. | 2014 Sep |
1 |
| 32 |
25253174 | Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial. | 2014 Nov |
3 |
| 33 |
25688512 | Rationale and protocol of the MetNET-1 trial, a prospective, single center, phase II study to evaluate the activity and safety of everolimus in combination with octreotide LAR and metformin in patients with advanced pancreatic neuroendocrine tumors. | 2014 Nov-Dec |
2 |
| 34 |
23620761 | Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners. | 2013 |
1 |
| 35 |
23663483 | Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells. | 2013 May 10 |
3 |
| 36 |
23794020 | Metabolic roles of AMPK and metformin in cancer cells. | 2013 Oct |
1 |
| 37 |
22038047 | Caveolin-1 is essential for metformin inhibitory effect on IGF1 action in non-small-cell lung cancer cells. | 2012 Feb |
5 |
| 38 |
21664031 | Does metformin influence the insulin-, IGF I- and IGF II-receptor gene expression and Akt phosphorylation in human decidualized endometrial stromal cells? | 2011 Oct |
3 |
| 39 |
21946410 | IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer. | 2011 Dec |
1 |
| 40 |
20363874 | AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. | 2010 Jun |
1 |
| 41 |
20388847 | Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. | 2010 May 1 |
2 |
| 42 |
18256928 | Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model. | 2009 Jan |
1 |
| 43 |
19709092 | Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris. | 2009 Oct |
1 |
| 44 |
17350746 | Effect of metformin on IGF-1 and IGFBP-1 levels in obese patients with polycystic ovary syndrome. | 2008 May |
1 |
| 45 |
18319306 | Metformin treatment for four years to reduce total and visceral fat in low birth weight girls with precocious pubarche. | 2008 May |
1 |
| 46 |
16492692 | Metformin therapy during puberty delays menarche, prolongs pubertal growth, and augments adult height: a randomized study in low-birth-weight girls with early-normal onset of puberty. | 2006 Jun |
1 |
| 47 |
16516166 | AMPK activation inhibits the expression of HIF-1alpha induced by insulin and IGF-1. | 2006 Apr 21 |
1 |
| 48 |
15063962 | Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome. | 2004 Apr 15 |
2 |
| 49 |
15697073 | Increased insulin-like growth factor-I levels in women with polycystic ovary syndrome, and beneficial effects of metformin therapy. | 2004 Sep |
5 |
| 50 |
12788862 | Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism. | 2003 Jun |
1 |