Title : Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome.

Pub. Date : 2004 Apr 15

PMID : 15063962






2 Functional Relationships(s)
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1 This study was designed to evaluate effects of metformin therapy on serum levels of IGFBP-1 and IGF-I. Metformin insulin like growth factor 1 Homo sapiens
2 CONCLUSIONS: The present study shows that metformin therapy not only restores normal levels of insulin and testosterone, but also decreases the pool of free-bioactive IGF-I by increasing the levels of circulating IGFBP-1. Metformin insulin like growth factor 1 Homo sapiens