Pub. Date : 2004 Sep
PMID : 15697073
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mean IGF-I levels decreased significantly on metformin therapy. | Metformin | insulin like growth factor 1 | Homo sapiens |
| 2 | Only the change in serum levels of progesterone and IGF-I on metformin were statistically significant between responders and non-responders; metformin-induced decremental change in IGF-I levels were greater in responders. | Metformin | insulin like growth factor 1 | Homo sapiens |
| 3 | Only the change in serum levels of progesterone and IGF-I on metformin were statistically significant between responders and non-responders; metformin-induced decremental change in IGF-I levels were greater in responders. | Metformin | insulin like growth factor 1 | Homo sapiens |
| 4 | By decreasing insulin and IGF-I levels, metformin therapy offers additional beneficial effects in resumption of regular menses. | Metformin | insulin like growth factor 1 | Homo sapiens |
| 5 | Thus, in PCOS patients with elevated levels of IGF-I, metformin may be considered as an appropriate agent to be used for the regulation of menstrual cycles. | Metformin | insulin like growth factor 1 | Homo sapiens |