| 1 |
33111621 | A molecular dynamics and docking study to screen anti-cancer compounds targeting mutated p53. | 2022 Apr |
1 |
| 2 |
35204825 | Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes. | 2022 Feb 18 |
2 |
| 3 |
35312310 | Nitrogen Mustard Alkylates and Cross-Links p53 in Human Keratinocytes. | 2022 Apr 18 |
2 |
| 4 |
35487360 | Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling. | 2022 Aug |
1 |
| 5 |
33357454 | Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. | 2021 Feb 8 |
2 |
| 6 |
33372419 | Association of hOGG1-Cys variants with occurrence of p53 and EGFR deletion mutations in non-small cell lung cancer. | 2021 Feb |
6 |
| 7 |
34386946 | Conjugation of Peptides to Gold Nanoparticles. | 2021 |
1 |
| 8 |
34679713 | p53 Forms Redox-Dependent Protein-Protein Interactions through Cysteine 277. | 2021 Oct 6 |
3 |
| 9 |
34683888 | Novel Nanocombinations of l-Tryptophan and l-Cysteine: Preparation, Characterization, and Their Applications for Antimicrobial and Anticancer Activities. | 2021 Oct 1 |
1 |
| 10 |
34831372 | Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms. | 2021 Nov 12 |
2 |
| 11 |
34862374 | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). | 2021 Dec 3 |
1 |
| 12 |
31945496 | Thiol antioxidants sensitize malabaricone C induced cancer cell death via reprogramming redox sensitive p53 and NF-κB proteins in vitro and in vivo. | 2020 Feb 20 |
1 |
| 13 |
32801360 | Autophagy activated by silibinin contributes to glioma cell death via induction of oxidative stress-mediated BNIP3-dependent nuclear translocation of AIF. | 2020 Aug 14 |
1 |
| 14 |
30728290 | Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity. | 2019 Feb 6 |
2 |
| 15 |
30892598 | p53 as a hub in cellular redox regulation and therapeutic target in cancer. | 2019 Apr 1 |
4 |
| 16 |
31601779 | Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277. | 2019 Oct 10 |
1 |
| 17 |
29670092 | APR-246 reactivates mutant p53 by targeting cysteines 124 and 277. | 2018 May 1 |
2 |
| 18 |
26870698 | Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy. | 2016 |
2 |
| 19 |
27479485 | Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins. | 2016 Sep 21 |
1 |
| 20 |
27551077 | 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. | 2016 Sep 6 |
1 |
| 21 |
25584637 | Oxidation of p53 through DNA charge transport involves a network of disulfides within the DNA-binding domain. | 2015 Jan 27 |
2 |
| 22 |
26086967 | APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells. | 2015 Jun 18 |
2 |
| 23 |
24446736 | Induction of lung cancer cell apoptosis through a p53 pathway by [6]-shogaol and its cysteine-conjugated metabolite M2. | 2014 Feb 12 |
1 |
| 24 |
25025378 | ERCC1 Cys8092Ala and XRCC1 Arg399Gln polymorphisms predict progression-free survival after curative radiotherapy for nasopharyngeal carcinoma. | 2014 |
1 |
| 25 |
23501101 | Redox state of p63 and p73 core domains regulates sequence-specific DNA binding. | 2013 Apr 19 |
1 |
| 26 |
23863845 | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. | 2013 Oct |
2 |
| 27 |
23038158 | The APE1 Asp/Asp genotype and the combination of APE1 Asp/Asp and hOGG1-Cys variants are associated with increased p53 mutation in non-small cell lung cancer. | 2012 |
3 |
| 28 |
21465572 | Redox modulation of p53: mechanisms and functional significance. | 2011 Apr |
1 |
| 29 |
21472523 | Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry. | 2011 May |
5 |
| 30 |
20208557 | 15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue. | 2010 Apr 29 |
4 |
| 31 |
20233844 | Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach. | 2010 Jul |
1 |
| 32 |
20459757 | Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivators. | 2010 May 10 |
1 |
| 33 |
20600834 | Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines. | 2010 Sep 1 |
2 |
| 34 |
20878668 | Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding. | 2010 Dec |
2 |
| 35 |
19101993 | Early detection of adrenocortical carcinoma in a child with Li-Fraumeni syndrome. | 2009 Apr |
1 |
| 36 |
19681600 | Effect of thioredoxin deletion and p53 cysteine replacement on human p53 activity in wild-type and thioredoxin reductase null yeast. | 2009 Sep 29 |
8 |
| 37 |
18179182 | Capture of p53 by electrodes modified with consensus DNA duplexes and amplified voltammetric detection using ferrocene-capped gold nanoparticle/streptavidin conjugates. | 2008 Feb 1 |
1 |
| 38 |
18502749 | Critical role of cysteine residue 81 of macrophage migration inhibitory factor (MIF) in MIF-induced inhibition of p53 activity. | 2008 Jul 18 |
4 |
| 39 |
18586825 | A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity. | 2008 Aug |
1 |
| 40 |
17070096 | Establishment and characterization of a tumorigenic cell line from areca quid and tobacco smoke-associated buccal carcinoma. | 2007 Aug |
1 |
| 41 |
17555331 | Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress. | 2007 Jul 3 |
5 |
| 42 |
17575104 | Suppression of cervical carcinoma cell growth by intracytoplasmic codelivery of anti-oncoprotein E6 antibody and small interfering RNA. | 2007 Jun |
1 |
| 43 |
17916563 | NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function. | 2007 Nov 30 |
5 |
| 44 |
16300733 | Recognition of cisplatin-damaged DNA by p53 protein: critical role of the p53 C-terminal domain. | 2006 Jan 13 |
1 |
| 45 |
15551330 | hOGG1 Ser326Cys polymorphism and G:C-to-T:A mutations: no evidence for a role in tobacco-related non small cell lung cancer. | 2005 Apr 10 |
11 |
| 46 |
15888975 | Pleomorphic carcinoma of the lung associated with loss of heterozygosity of p53 gene. | 2005 Jun |
1 |
| 47 |
15105503 | Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. | 2004 Apr 23 |
1 |
| 48 |
15154850 | The CBP/p300 TAZ1 domain in its native state is not a binding partner of MDM2. | 2004 Aug 1 |
1 |
| 49 |
15274301 | Selenium compounds regulate p53 by common and distinctive mechanisms. | 2004 May-Jun |
2 |
| 50 |
12663048 | Activation of p53 by the cytoprotective aminothiol WR1065: DNA-damage-independent pathway and redox-dependent modulation of p53 DNA-binding activity. | 2003 Apr 1 |
2 |