Pub. Date : 2012
PMID : 23038158
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The APE1 Asp/Asp genotype and the combination of APE1 Asp/Asp and hOGG1-Cys variants are associated with increased p53 mutation in non-small cell lung cancer. | Cysteine | tumor protein p53 | Homo sapiens |
2 | The risk of p53 mutation was also higher in participants with APE1 Asp/Asp plus hOGG1-Cys than in those with APE1-Glu plus hOGG1 Ser/Ser (OR, 3.72; 95% CI, 1.33-10.40; P = 0.012). | Cysteine | tumor protein p53 | Homo sapiens |
3 | CONCLUSIONS: These results suggest that the APE1 Asp/Asp genotype and the combination of the APE1 Asp/Asp and hOGG1-Cys variants are associated with increased risk of p53 mutation in non-small cell lung cancer. | Cysteine | tumor protein p53 | Homo sapiens |