Pub. Date : 2016
PMID : 26870698
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | One of these molecules, APR-246, is a prodrug that is converted to the Michael acceptor methylene quinuclidinone (MQ) that binds covalently to cysteines in p53, leading to refolding and restoration of wild type p53 function. | Cysteine | tumor protein p53 | Homo sapiens |
2 | One of these molecules, APR-246, is a prodrug that is converted to the Michael acceptor methylene quinuclidinone (MQ) that binds covalently to cysteines in p53, leading to refolding and restoration of wild type p53 function. | Cysteine | tumor protein p53 | Homo sapiens |