Title : Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.

Pub. Date : 2013 Oct

PMID : 23863845






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 A p53 hot-spot mutation found frequently in human cancer is the replacement of R273 by histidine or cysteine residues resulting in p53 loss of function as a tumor suppressor. Cysteine tumor protein p53 Homo sapiens
2 A p53 hot-spot mutation found frequently in human cancer is the replacement of R273 by histidine or cysteine residues resulting in p53 loss of function as a tumor suppressor. Cysteine tumor protein p53 Homo sapiens