Title : Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD.

Pub. Date : 2004 Apr 23

PMID : 15105503






1 Functional Relationships(s)
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1 We show that sestrins, a family of proteins whose expression is modulated by p53, are required for regeneration of Prxs containing Cys-SO(2)H, thus reestablishing the antioxidant firewall. Cysteine tumor protein p53 Homo sapiens