| 1 |
34752647 | Association of CYP2B6 genetic polymorphisms with bupropion and hydroxybupropion exposure: A systematic review and meta-analysis. | 2022 Jan |
7 |
| 2 |
34791718 | Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion-aided smoking cessation in African Americans? A moderated mediation analysis. | 2022 Jun |
3 |
| 3 |
34910929 | Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. | 2022 Jan 25 |
1 |
| 4 |
35194103 | CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function. | 2022 Feb 22 |
1 |
| 5 |
32648334 | Characterization of the Effect of Upadacitinib on the Pharmacokinetics of Bupropion, a Sensitive Cytochrome P450 2B6 Probe Substrate. | 2021 Mar |
2 |
| 6 |
33599403 | Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population. | 2021 Mar |
1 |
| 7 |
33739838 | Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes. | 2021 Apr 5 |
1 |
| 8 |
33806634 | Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network. | 2021 Mar 4 |
4 |
| 9 |
32238417 | Stereoselective Bupropion Hydroxylation by Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase Genetic Variants. | 2020 Jun |
12 |
| 10 |
32364297 | Deoxyshikonin reversibly inhibits cytochrome P450 2B6. | 2020 Apr |
2 |
| 11 |
32475982 | Subtherapeutic bupropion and hydroxybupropion serum concentrations in a patient with CYP2C19*1/*17 genotype suggesting a rapid metabolizer status. | 2020 Dec |
1 |
| 12 |
33124517 | Nonresponse to high-dose bupropion for depression in a patient carrying CYP2B6*6 and CYP2C19*17 variants: a case report. | 2020 Nov |
3 |
| 13 |
29756345 | Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition. | 2019 Jan |
9 |
| 14 |
30472588 | In vivo phenotyping of cytochrome 450 isoforms involved in the metabolism of anti-HIV and anti-tubercular drugs in human using cocktail approach: An LC-MS/MS analysis. | 2019 Feb 5 |
2 |
| 15 |
30578565 | Role of CYP2B6 pharmacogenomics in bupropion-mediated smoking cessation. | 2019 Apr |
7 |
| 16 |
28737446 | Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims. | 2018 Jul |
3 |
| 17 |
28876959 | Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion. | 2018 Sep |
2 |
| 18 |
29637923 | Effects of Genetic Polymorphisms of CYP2B6 on the Pharmacokinetics of Bupropion and Hydroxybupropion in Healthy Chinese Subjects. | 2018 Apr 11 |
1 |
| 19 |
29870591 | Amenamevir: Studies of Potential CYP2C8- and CYP2B6-Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers. | 2018 Nov |
1 |
| 20 |
30201214 | Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation. | 2018 Oct |
2 |
| 21 |
28468305 | Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes. | 2017 May 1 |
1 |
| 22 |
26580670 | Effects of the selected cytochrome P450 oxidoreductase genetic polymorphisms on cytochrome P450 2B6 activity as measured by bupropion hydroxylation. | 2016 Feb |
7 |
| 23 |
26802129 | Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo. | 2016 Apr |
1 |
| 24 |
27128896 | Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. | 2016 Apr 27 |
1 |
| 25 |
27387538 | Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6. | 2016 Aug 25 |
2 |
| 26 |
27422672 | Evaluation of CYP2B6 Induction and Prediction of Clinical Drug-Drug Interactions: Considerations from the IQ Consortium Induction Working Group-An Industry Perspective. | 2016 Oct |
1 |
| 27 |
27435752 | Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6. | 2016 Jul |
1 |
| 28 |
27439448 | The P450 oxidoreductase (POR) rs2868177 and cytochrome P450 (CYP) 2B6*6 polymorphisms contribute to the interindividual variability in human CYP2B6 activity. | 2016 Oct |
2 |
| 29 |
27495292 | Stereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4'-OH-bupropion in vitro. | 2016 Oct |
4 |
| 30 |
27528039 | Pharmacokinetics of Bupropion and Its Pharmacologically Active Metabolites in Pregnancy. | 2016 Nov |
2 |
| 31 |
27660681 | Identification and Structural Characterization of Three New Metabolites of Bupropion in Humans. | 2016 Aug 11 |
1 |
| 32 |
25409894 | Characterization of CYP2B6 in a CYP2B6-humanized mouse model: inducibility in the liver by phenobarbital and dexamethasone and role in nicotine metabolism in vivo. | 2015 Feb |
1 |
| 33 |
25489907 | CYP2B6 gene single-nucleotide polymorphisms in an Italian population sample and relationship with nicotine dependence. | 2015 Feb |
1 |
| 34 |
25565674 | Effect of CYP2B6*6 on Steady-State Serum Concentrations of Bupropion and Hydroxybupropion in Psychiatric Patients: A Study Based on Therapeutic Drug Monitoring Data. | 2015 Oct |
4 |
| 35 |
25656918 | Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction. | 2015 Mar 25 |
3 |
| 36 |
25801005 | Influence of HIV antiretrovirals on methadone N-demethylation and transport. | 2015 May 15 |
1 |
| 37 |
25904761 | Metabolism of bupropion by carbonyl reductases in liver and intestine. | 2015 Jul |
3 |
| 38 |
26055126 | Selective inhibitory effects of machilin A isolated from Machilus thunbergii on human cytochrome P450 1A and 2B6. | 2015 Jun 1 |
1 |
| 39 |
26153084 | CYP2B6 rs2279343 polymorphism is associated with smoking cessation success in bupropion therapy. | 2015 Sep |
6 |
| 40 |
26681005 | Prevalence of CYP2B6 polymorphisms in Argentinians: the role of genetic testing. | 2015 Dec 11 |
1 |
| 41 |
24423593 | Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma. | 2014 Jan |
1 |
| 42 |
24452068 | Serum concentrations of hydroxybupropion for dose optimization of depressed patients treated with bupropion. | 2014 Aug |
1 |
| 43 |
24658455 | Investigational small-molecule drug selectively suppresses constitutive CYP2B6 activity at the gene transcription level: physiologically based pharmacokinetic model assessment of clinical drug interaction risk. | 2014 Jun |
1 |
| 44 |
25309681 | Structure-Activity Studies Reveal the Oxazinone Ring Is a Determinant of Cytochrome P450 2B6 Activity Toward Efavirenz. | 2014 Oct 9 |
3 |
| 45 |
23153057 | Assessment of cytochrome P450 (1A2, 2B6, 2C9 and 3A4) induction in cryopreserved human hepatocytes cultured in 48-well plates using the cocktail strategy. | 2013 Apr |
1 |
| 46 |
23238783 | The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans. | 2013 Mar |
5 |
| 47 |
23245243 | A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS. | 2013 Feb 23 |
1 |
| 48 |
23344581 | Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state. | 2013 Mar |
4 |
| 49 |
23467454 | Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance. | 2013 |
1 |
| 50 |
23648676 | Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia. | 2013 |
1 |