Title : Influence of HIV antiretrovirals on methadone N-demethylation and transport.

Pub. Date : 2015 May 15

PMID : 25801005






1 Functional Relationships(s)
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1 CYP2B6 mRNA and activity (bupropion N-demethylation) were induced by several antiretrovirals, as were CYP3A4 mRNA and protein expression, but only indinavir increased CYP3A activity (alfentanil dealkylation). Bupropion cytochrome P450 family 2 subfamily B member 6 Homo sapiens