Pub. Date : 2021 Mar
PMID : 32648334
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterization of the Effect of Upadacitinib on the Pharmacokinetics of Bupropion, a Sensitive Cytochrome P450 2B6 Probe Substrate. | Bupropion | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | This phase 1 study characterized the effect of multiple doses of upadacitinib, an oral Janus kinase 1 selective inhibitor, on the pharmacokinetics of the cytochrome P450 (CYP) 2B6 substrate bupropion. | Bupropion | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |