Title : The P450 oxidoreductase (POR) rs2868177 and cytochrome P450 (CYP) 2B6*6 polymorphisms contribute to the interindividual variability in human CYP2B6 activity.

Pub. Date : 2016 Oct

PMID : 27439448






2 Functional Relationships(s)
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1 CYP2B6 activity was measured by bupropion hydroxylation with LC/MS/MS. Bupropion cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 The ratio of hydroxybupropion versus bupropion (AUC_hyd/AUC_bup) in terms of area under the time-concentration curve (AUC) was used to represent the CYP2B6 activity. Bupropion cytochrome P450 family 2 subfamily B member 6 Homo sapiens