Tacrolimus

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







240 Article(s)
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201 15951320 Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus. 2005 Aug 4
202 16038570 Pharmacokinetic considerations relating to tacrolimus dosing in the elderly. 2005 2
203 16100295 Concomitant tacrolimus and micafungin pharmacokinetics in healthy volunteers. 2005 Sep 1
204 16146556 Influence of CYP3A5 and MDR1 polymorphisms on tacrolimus concentration in the early stage after renal transplantation. 2005 Oct 1
205 15010519 Lansoprazole-tacrolimus interaction in Japanese transplant recipient with CYP2C19 polymorphism. 2004 May 2
206 15197524 Gene expression of cytochromes P450 in liver transplants over time. 2004 Aug 3
207 15307840 CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus. 2004 Sep 3
208 15340245 Increased bioavailability of tacrolimus after rectal administration in rats. 2004 Sep 1
209 15350151 Drug interactions with St John's wort : mechanisms and clinical implications. 2004 1
210 15383495 The rate of gastric emptying determines the timing but not the extent of oral tacrolimus absorption: simultaneous measurement of drug exposure and gastric emptying by carbon-14-octanoic acid breath test in stable renal allograft recipients. 2004 Dec 1
211 15518758 Increased tacrolimus trough levels in association with severe diarrhea, a case report. 2004 Sep 1
212 15570183 Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5. 2004 Dec 1
213 12694072 Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms. 2003 Apr 1
214 12826147 Coadministration of tacrolimus and ketoconazole in renal transplant recipients: cost analysis and review of metabolic effects. 2003 Jun 1
215 12966368 Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus. 2003 Sep 5
216 14551375 Pharmacokinetic interaction between corticosteroids and tacrolimus after renal transplantation. 2003 Nov 2
217 14578760 Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients. 2003 Oct 27 1
218 14632538 Tacrolimus and lopinavir/ritonavir interaction in liver transplantation. 2003 Dec 1
219 14870897 Tacrolimus dosage requirements after initiation of azole antifungal therapy in pediatric thoracic organ transplantation. 2003 Dec 1
220 11923712 Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort. 2002 Mar 27 1
221 12167066 Drug interactions with tacrolimus. 2002 1
222 12190331 Mechanisms of clinically relevant drug interactions associated with tacrolimus. 2002 5
223 12451243 Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. 2002 Nov 27 2
224 12497749 [Interaction between sildenafil and calcineurin inhibitors in renal transplant recipients with erectile dysfunction]. 2002 1
225 12685503 In vitro effects of tacrolimus on human cytochrome P450. 2002 Dec 3
226 11239516 Preliminary report on the effect of xenoperfusion with human blood on cyclosporin A metabolism and cytochrome-P-4503A4-mRNA expression in a pig liver perfusion model. 2001 Feb 1
227 11397967 The effect of gut metabolism on tacrolimus bioavailability in renal transplant recipients. 2001 May 15 2
228 11719731 Early postoperative erythromycin breath test correlates with hepatic cytochrome P4503A activity in liver transplant recipients. 2001 Nov 2
229 10731062 Increased tacrolimus levels in a pediatric renal transplant patient attributed to chronic diarrhea. 2000 Feb 1
230 9987705 Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers. 1999 Jan 1
231 10410178 Diltiazem increases tacrolimus concentrations. 1999 Jun 1
232 10440408 Concomitant human immunodeficiency virus protease inhibitor therapy markedly reduces tacrolimus metabolism and increases blood levels. 1999 Jul 27 1
233 9808496 Relationship between in vivo FK506 clearance and in vitro 13-demethylation activity in living-related liver transplantation. 1998 Oct 27 1
234 9808502 Serious interaction between mibefradil and tacrolimus. 1998 Oct 27 1
235 9246018 Tacrolimus oral bioavailability doubles with coadministration of ketoconazole. 1997 Jul 1
236 10837558 Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. 1997 Sep 15 3
237 8857552 Erythromycin breath test and clinical transplantation. 1996 Aug 1
238 7552894 Tacrolimus: a new immunosuppressive agent. 1995 Jul 15 1
239 7628296 Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125. 1995 Mar 1
240 8689938 Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. 1995 Dec 6