Title : Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms.

Pub. Date : 2003 Apr

PMID : 12694072






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 P-gp is encoded by the multiple drug resistance gene MDR1 and CYP3A is the major enzyme responsible for tacrolimus metabolism. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens