Title : NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells.

Pub. Date : 2010 Jan

PMID : 19943112






1 Functional Relationships(s)
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1 Interestingly, selective inactivation of NF-kappaB using either an NF-kappaB decoy or parthenolide, a blocker of IKK-dependent NF-kappaB activation, reduced, rather then increased, apoptosis and p53 levels in FC1-depleted cells. parthenolide nuclear factor kappa B subunit 1 Homo sapiens