parthenolide

nuclear factor kappa B subunit 1 ; Homo sapiens







95 Article(s)
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51 20701602 The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells. 2010 Oct 1
52 20702415 MTA1 coregulator regulates LPS response via MyD88-dependent signaling. 2010 Oct 22 1
53 20718930 NF-κB is not directly responsible for photoresistance induced by fractionated light delivery in HT-29 colon adenocarcinoma cells. 2010 Nov-Dec 1
54 19397439 Suppression of NF-kappaB activity by parthenolide induces X-ray sensitivity through inhibition of split-dose repair in TP53 null prostate cancer cells. 2009 Apr 5
55 19404004 [Application of NFkappaB inhibitor for arthritis]. 2009 Apr 1
56 19584059 Nuclear factor-kappaB regulates estrogen receptor-alpha transcription in the human heart. 2009 Sep 11 1
57 19956548 Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide. 2009 Dec 2 1
58 20224758 Cardiotrophin-1 induces tumor necrosis factor alpha synthesis in human peripheral blood mononuclear cells. 2009 2
59 18347184 Antimyeloma effects of a sesquiterpene lactone parthenolide. 2008 Mar 15 1
60 18425350 Thermosensitization by parthenolide in human lung adenocarcinoma A549 cells and p53- and hsp72-independent apoptosis induction via the nuclear factor-kappaB signal pathway. 2008 May 6
61 18652825 Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. 2008 Oct 1 3
62 19023456 TNFalpha-induced activation of NFkappaB protects against UV-induced apoptosis specifically in p53-proficient cells. 2008 1
63 19116667 Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription. 2008 2
64 17290398 Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappaB. 2007 Jun 15 7
65 17325184 RAGE ligand upregulation of VEGF secretion in ARPE-19 cells. 2007 Mar 1
66 18088190 Parthenolide sensitizes cells to X-ray-induced cell killing through inhibition of NF-kappaB and split-dose repair. 2007 Dec 3
67 16002075 C-reactive protein induces VCAM-1 gene expression through NF-kappaB activation in vascular endothelial cells. 2006 Mar 1
68 16705314 Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01. 2006 May 22 6
69 16733051 Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines. 2006 Aug 1 1
70 16873071 Estrogen dependent growth inhibitory effects of tamoxifen but not genistein in solid tumors derived from estrogen receptor positive (ER+) primary breast carcinoma MCF7: single agent and novel combined treatment approaches. 2006 Jul 1
71 16878028 Activation of common antiviral pathways can potentiate inflammatory responses to septic shock. 2006 Aug 2
72 16921510 Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model. 2006 Oct 1 4
73 17259561 Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications. 2006 Dec 1
74 15657351 The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells. 2005 Jan 2
75 15743683 Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers. 2005 May 4
76 15827332 Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. 2005 Apr 4
77 15956258 The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer. 2005 Jun 4
78 16043032 Altered NF-kappaB gene expression and collagen formation induced by polyunsaturated fatty acids. 2005 Aug 2
79 15015572 Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest. 2004 Jan-Feb 2
80 15183076 Role of cysteine residues of p65/NF-kappaB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential. 2004 Jul 2 1
81 15256485 Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells. 2004 Nov 1
82 15328189 Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate. 2004 Aug 15 3
83 15467918 Fibrinogen regulates the expression of inflammatory chemokines through NF-kappaB activation of endothelial cells. 2004 Oct 1
84 12570770 Ethnobotany and natural products: the search for new molecules, new treatments of old diseases or a better understanding of indigenous cultures? 2003 1
85 12851492 Cell cycle effects and caspase-dependent and independent death of HL-60 and Jurkat cells treated with the inhibitor of NF-kappaB parthenolide. 2003 Jul-Aug 1
86 11877332 Enhancement of 1 alpha,25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kappa B activity. 2002 Mar 3
87 11921057 Nuclear factor-kappaB as a molecular target for migraine therapy. 2002 Apr 1
88 12067985 Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780). 2002 Jun 15 1
89 11360202 Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death. 2001 Apr 19 1
90 11428868 Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells. 2001 Jul 1
91 11500489 Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. 2001 Oct 26 2
92 11588049 Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor kappaB-mediated antiapoptosis involving c-IAP2. 2001 Oct 15 2
93 11598079 Survival of Chlamydia pneumoniae-infected Mono Mac 6 cells is dependent on NF-kappaB binding activity. 2001 Nov 1
94 10704251 Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium. 2000 Mar 2
95 10553091 The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. 1999 Nov 15 4