Tyrosine

insulin receptor substrate 1 ; Mus musculus







208 Article(s)
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1 35426803 [CD36 gene deletion reduces muscle insulin sensitivity in mice by up-regulating PTP1B expression]. 2022 Mar 20 2
2 34203825 Short-Term Strength Exercise Reduces Hepatic Insulin Resistance in Obese Mice by Reducing PTP1B Content, Regardless of Changes in Body Weight. 2021 Jun 15 1
3 34769439 IL-4 and IL-13 Promote Proliferation of Mammary Epithelial Cells through STAT6 and IRS-1. 2021 Nov 5 5
4 31829469 NK cells induce hepatic ER stress to promote insulin resistance in obesity through osteopontin production. 2020 Apr 2
5 32588693 DPP-4 inhibition resembles exercise in preventing type 2 diabetes development by inhibiting hepatic protein kinase Cε expression in a mouse model of hyperinsulinemia. 2020 Jun 1
6 33208251 Protective effect of the hydroalcoholic extract from Lampaya medicinalis Phil. (Verbenaceae) on palmitic acid- impaired insulin signaling in 3T3-L1 adipocytes. 2020 Nov - Dec 1
7 31660449 Dietary Exposure to Transgenic Rice Expressing the Spider Silk Protein Fibroin Reduces Blood Glucose Levels in Diabetic Mice: The Potential Role of Insulin Receptor Substrate-1 Phosphorylation in Adipocytes. 2019 Sep 1
8 31705915 NLRP3 inflammasome mediate palmitate-induced endothelial dysfunction. 2019 Dec 15 1
9 31802924 Dihydromyricetin Attenuates Metabolic Syndrome And Improves Insulin Sensitivity By Upregulating Insulin Receptor Substrate-1 (Y612) Tyrosine Phosphorylation In db/db Mice. 2019 2
10 29374854 Liraglutide ameliorates palmitate-induced insulin resistance through inhibiting the IRS-1 serine phosphorylation in mouse skeletal muscle cells. 2018 Sep 1
11 30050584 QiDiTangShen Granules Reduced Diabetic Kidney Injury by Regulating the Phosphorylation Balance of the Tyrosine and Serine Residues of Insulin Receptor Substrate 1. 2018 1
12 30252210 Myostatin inhibits glucose uptake via suppression of insulin-dependent and -independent signaling pathways in myoblasts. 2018 Sep 1
13 27462872 Nandinine, a Derivative of Berberine, Inhibits Inflammation and Reduces Insulin Resistance in Adipocytes via Regulation of AMP-Kinase Activity. 2017 Feb 1
14 27913296 Regulation of skeletal muscle insulin-stimulated signaling through the MEK-REDD1-mTOR axis. 2017 Jan 22 2
15 28386117 Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's disease. 2017 Apr 6 1
16 28941626 Deletion of protein tyrosine phosphatase 1B obliterates endoplasmic reticulum stress-induced myocardial dysfunction through regulation of autophagy. 2017 Dec 1
17 26328540 Combination of PKCε Activation and PTP1B Inhibition Effectively Suppresses Aβ-Induced GSK-3β Activation and Tau Phosphorylation. 2016 Sep 2
18 26773517 IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation. 2016 Jun 1
19 26827782 Phycocyanin ameliorates alloxan-induced diabetes mellitus in mice: Involved in insulin signaling pathway and GK expression. 2016 Mar 5 1
20 26846849 Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase. 2016 Apr 15 1
21 26976654 Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS)1(-/-), and IRS2(-/-) male mice fed a high-fat diet. 2016 May 1
22 27090933 Ursolic acid and rosiglitazone combination improves insulin sensitivity by increasing the skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat diet-fed C57BL/6J mice. 2016 Jun 1
23 27251941 The phosphatidylethanolamine derivative diDCP-LA-PE mimics intracellular insulin signaling. 2016 Jun 2 1
24 25689493 N-myristoylated ubiquitin ligase Cbl-b inhibitor prevents on glucocorticoid-induced atrophy in mouse skeletal muscle. 2015 Mar 15 3
25 25912041 Ginseng berry extract supplementation improves age-related decline of insulin signaling in mice. 2015 Apr 22 1
26 26079879 Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. 2015 Aug 7 2
27 24530856 Cyclocarya paliurus extract modulates adipokine expression and improves insulin sensitivity by inhibition of inflammation in mice. 2014 Apr 28 1
28 24599575 Coffee intake mitigated inflammation and obesity-induced insulin resistance in skeletal muscle of high-fat diet-induced obese mice. 2014 May 2
29 24925305 The anti-diabetic activity of Bifidobacterium lactis HY8101 in vitro and in vivo. 2014 Sep 1
30 25174657 Phytic acid and myo-inositol support adipocyte differentiation and improve insulin sensitivity in 3T3-L1 cells. 2014 Aug 1
31 22843013 Opposite effects of quercetin, luteolin, and epigallocatechin gallate on insulin sensitivity under normal and inflammatory conditions in mice. 2013 Feb 2
32 22941977 Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle. 2013 Feb 1
33 22983867 Swim training of monosodium L-glutamate-obese mice improves the impaired insulin receptor tyrosine phosphorylation in pancreatic islets. 2013 Jun 2
34 23313043 Glyceollin improves endoplasmic reticulum stress-induced insulin resistance through CaMKK-AMPK pathway in L6 myotubes. 2013 Jun 3
35 23316967 An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice. 2013 Mar 1 1
36 23493568 X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function. 2013 Jul 2
37 23565163 Phosphorylation of IRS1 at serine 307 in response to insulin in human adipocytes is not likely to be catalyzed by p70 ribosomal S6 kinase. 2013 1
38 23627466 Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat-high-fructose diet-fed mice. 2013 Jul 2
39 23639858 Paraoxonase1 (PON1) reduces insulin resistance in mice fed a high-fat diet, and promotes GLUT4 overexpression in myocytes, via the IRS-1/Akt pathway. 2013 Jul 1
40 23763311 Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue. 2013 Sep 2
41 23886629 The Akt substrate Girdin is a regulator of insulin signaling in myoblast cells. 2013 Dec 1
42 23946430 Pioglitazone does not improve insulin signaling in mice with GH over-expression. 2013 Nov 1
43 24061149 Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant mice. 2013 Nov 1
44 22188104 Exercise-induced muscle damage impairs insulin signaling pathway associated with IRS-1 oxidative modification. 2012 1
45 22198320 St. John's Wort inhibits insulin signaling in murine and human adipocytes. 2012 Apr 1
46 22215652 Selective PPARγ modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice. 2012 Mar 1 1
47 22418434 Muscle-specific knock-out of NUAK family SNF1-like kinase 1 (NUAK1) prevents high fat diet-induced glucose intolerance. 2012 May 11 1
48 22761437 Sequestosome 1/p62, a scaffolding protein, is a newly identified partner of IRS-1 protein. 2012 Aug 24 3
49 22832498 Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice. 2012 Oct 1
50 22864348 [Retinoids as promising treatment for non-alcoholic fatty liver disease]. 2012 1