Title : IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation.

Pub. Date : 2016 Jun

PMID : 26773517






1 Functional Relationships(s)
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Protein Name
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1 Peptides that disrupted p62/PKCzeta or p62/IRS-1 inhibited IGF-I/IGFBP-2 stimulated PKCzeta activation, vimentin phosphorylation, PTEN tyrosine phosphorylation, AKT activation, and osteoblast differentiation. Tyrosine insulin receptor substrate 1 Mus musculus